ArticleThe Journal of veterinary medical science2023
Effect of live yeast Saccharomyces cerevisiae supplementation on immune factors in Japanese Black calves during the growth periods.
Article in The Journal of veterinary medical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Effects of composite probiotics on growth performance, diarrhea rate, and serum indicators in newborn Holstein calves.Animal bioscience · 2026Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to investigate changes in expression levels of immune factors of peripheral blood mononuclear cells (PBMC) after oral supplementation of live yeast Saccharomyces cerevisiae to healthy Japanese Black (JB) calves. This study examined JB calves (N=28): 14 calves (SC Group) received 10 g/calf/day of Saccharomyces cerevisiae (SC) (Acti-Saf Sc 47), and the other calves did not receive supplement (Control Group). Blood samples were collected 9 times during experimental period (1, 2, 3, 4, 5, 6, 7, 8 and 9 months of age), and analyzed for cytokines and chemokines mRNA expression of PBMC using Real-time PCR. The level of beta Hydroxybutanoic acid (BHB) in the SC Group was significantly high at 7 and 8 months of age compared to that in the Control Group. Lymphocyte counts in the SC Group were significantly higher at 2 and 5 to 6 months of age compared to the Control Group. Significant differences were found for IL-12p40 level at 4, 7 and 9 months of age, and for IFN-γ level at 6, 7 and 8 months of age. The level of CXCR3 was significantly higher at 6 to 7 months of age by dietary SC supplementation. These results indicated that SC supplementation improved the cellular immune responses of JB calves.
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