Evidence map›Paper›PMID 36682343›Full record

Trial reportThe Journal of surgical research2023

Evaluation of Preoperative and Intraoperative Mobile Gamma Camera Imaging in Sentinel Lymph Node Biopsy for Melanoma Independent of Preoperative Lymphoscintigraphy.

Joshua M Judge, Kosta Popovic, Gina R Petroni, Brian Kross, John McKisson, Jack McKisson, Andrew G Weisenberger, Alexander Stolin, Stan Majewski, Patrice Rehm and 3 more

Registry-linked trialOpen access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Journal of surgical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01531608 (Evaluation Of Mobile Gamma Camera Imaging For Sentinel Node Biopsy In Melanoma Independent Of Fixed Gamma Camera Imaging), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01531608 completednot on this map

Evaluation Of Mobile Gamma Camera Imaging For Sentinel Node Biopsy In Melanoma Independent Of Fixed Gamma Camera Imaging

TypeobservationalSponsorUniversity of VirginiaRan2011 to 2012Enrolled20ConditionsMelanoma
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Nuclear medicine in the operating room: present and future.The British journal of radiology · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Joshua M JudgeDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Kosta PopovicDepartment of Physics, University of Virginia, Charlottesville, Virginia.
Gina R PetroniDepartment of Public Health Sciences, University of Virginia, Charlottesville, Virginia.
Brian KrossPhysics Division, Radiation Detector and Imaging Group, Thomas Jefferson National Accelerator Facility, Newport News, Virginia.
John McKissonPhysics Division, Radiation Detector and Imaging Group, Thomas Jefferson National Accelerator Facility, Newport News, Virginia.
Jack McKissonPhysics Division, Radiation Detector and Imaging Group, Thomas Jefferson National Accelerator Facility, Newport News, Virginia.
Andrew G WeisenbergerPhysics Division, Radiation Detector and Imaging Group, Thomas Jefferson National Accelerator Facility, Newport News, Virginia.
Alexander StolinDepartment of Radiology, West Virginia University, Morgantown, West Virginia.
Stan MajewskiDepartment of Radiology, West Virginia University, Morgantown, West Virginia.
Patrice RehmDepartment of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia.
Craig L SlingluffDepartment of Surgery, University of Virginia, Charlottesville, Virginia.
Mark B WilliamsDepartment of Physics, University of Virginia, Charlottesville, Virginia; Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia; Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia.
Lynn T DengelDepartment of Surgery, University of Virginia, Charlottesville, Virginia. Electronic address: ltd5b@virginia.edu.
University of Virginia · USThomas Jefferson National Accelerator Facility · USWest Virginia University · USUniversity of Virginia Medical Center · US

Funding

Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Thomas P. Loughran · 1987 to 2026
$72.1M
Postdoctoral Training Grant for MDs in Surgical Oncology ResearchT32CA163177 · NCI · UNIVERSITY OF VIRGINIA · PI Craig Lee Slingluff, Allan Tsung · 2011 to 2026
$4.6M
NCI NIH HHS P30 CA044579NCI NIH HHS T32 CA163177
6 · The paper itself

Abstract

introductionSentinel lymph node biopsy (SLNB) is a standard practice for staging cutaneous melanoma. High false-negative rates have an increased interest in adjunctive techniques for localizing SLNs. Mobile gamma cameras (MGCs) represent potential tools to enhance SLNB performance.

methodsAn institutional review board approval was obtained for this study (ClinicalTrials.gov ID NCT01531608). After obtaining informed consent, 20 eligible melanoma patients underwent

resultsA total of 24 SLN basins were detected by FGC. Prior to unblinding, all 24 basins were identified with the preoperative MGC and the operative plan established by preoperative MGC imaging was confirmed accurate by review of the FGC images. All individual sentinel lymph nodes were identified during intraoperative MGC imaging, and in 5/24 (21%) cases, surgeon-reported additional clinically useful information was obtained from the MGC.

conclusionsPreoperative MGC images provide information consistent with FGC images for planning SLNB and in some cases provide additional information that aided in surgical decision-making.

Indexed as

MelanomaSkin NeoplasmsGamma CamerasHumansLymph NodesLymphoscintigraphyRadiopharmaceuticalsSentinel Lymph Node BiopsyTechnetium Tc 99m Sulfur ColloidRadiopharmaceuticalsTechnetium Tc 99m Sulfur ColloidGamma cameraImage-guided surgeryMelanomaNuclear medicineSentinel lymph node biopsyTechnetium Tc 99m sulfur colloid

Identifiers

PMID36682343
PMCPMC11283632
OpenAlexW4317566491

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.