Evidence map›Paper›PMID 36682280›Full record

ArticleJournal of inorganic biochemistry2023

Solution phase refinement of active site structure using 2D NMR and judiciously

Remigio Usai, Daniel Kaluka, Sheng Cai, Daniel S Sem, James R Kincaid

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of inorganic biochemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Remigio UsaiDepartment of Chemistry, Marquette University, Wisconsin 53233, United States.
Daniel KalukaDepartment of Chemistry and Biochemistry, Taylor University, Upland, IN 46989, United States.
Sheng CaiSchool of Pharmacy, University of Wisconsin Madison, Madison, WI 53705, United States.
Daniel S SemDepartment of Pharmaceutical Sciences, Concordia University of Wisconsin, Mequon, WI 53097, United States. Electronic address: daniel.sem@cuw.edu.
James R KincaidDepartment of Chemistry, Marquette University, Wisconsin 53233, United States.
Marquette University · USConcordia University · USTaylor University · USUniversity of Wisconsin–Madison · US

Funding

Mechanisms and control of multifunctional cytochromes P450R01GM125303 · NIGMS · MARQUETTE UNIVERSITY · PI KINCAID, JAMES ROBERT · 2017 to 2020
$1.0M
NIGMS NIH HHS R01 GM125303
6 · The paper itself

Abstract

The Cytochrome P450 (CYP450) superfamily has been the subject of intense research for over six decades. Here the HU227 strain of E. coli, lacking the δ-aminolevulinic acid (δ-ALA) synthase gene, was employed, along with [5-

Indexed as

Camphor 5-MonooxygenaseProtonsBinding SitesCatalytic DomainCytochrome P-450 Enzyme SystemEscherichia coliCamphor 5-MonooxygenaseCytochrome P-450 Enzyme SystemProtons2D (13)C-filtered NOESY-HMQCALA synthesisCytochrome P450Docking proceduresHeme proteinsHU227 E. coli strain

Identifiers

PMID36682280
PMCPMC10725731
OpenAlexW4316038215

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.