Evidence map›Paper›PMID 36682226›Full record

ReviewJournal of clinical anesthesia2023

Perioperative implications of patients with alpha gal allergies.

Maziar M Nourian, Cosby A Stone, Kara K Siegrist, Matthias L Riess

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical anesthesia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Neurosurgical Management of Patients with Alpha-Gal Syndrome.Journal of neurological surgery reports · 2024
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maziar M NourianDepartment of Anesthesiology, Vanderbilt University Medical Center, 1161 21(st) Avenue South, Nashville, TN 37232, USA. Electronic address: maziarnourian@gmail.com.
Cosby A StoneDepartment of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232, USA. Electronic address: cosby.a.stone@vumc.org.
Kara K SiegristDepartment of Anesthesiology, Vanderbilt University Medical Center, 1161 21(st) Avenue South, Nashville, TN 37232, USA. Electronic address: kara.k.siegrist@vumc.org.
Matthias L RiessDepartment of Anesthesiology, Vanderbilt University Medical Center, 1161 21(st) Avenue South, Nashville, TN 37232, USA; Anesthesiology, Tennessee Valley Healthcare System Veterans Affairs Medical Center, 1310 24(th) Ave South, Nashville, TN 37212, USA; Department of Pharmacology, Vanderbilt University, 465 21(st) Avenue South, Nashville, TN 37232, USA. Electronic address: matthias.riess@vanderbilt.edu.
Vanderbilt University Medical Center · US

Funding

Novel Copolymer-based Cell Membrane Stabilizers to Attenuate Myocardial InfarctionI01BX003482 · VA · VETERANS HEALTH ADMINISTRATION · PI RIESS, MATTHIAS L. · 2018 to 2022
–
BLRD VA I01 BX003482
6 · The paper itself

Abstract

Alpha Gal Syndrome (AGS) is an emerging immune response to mammalian products (MP) containing the oligosaccharide galactose-α-1,3 galactose (α-Gal) which includes meats and inactive ingredients in certain medications. This becomes clinically important in the perioperative realm as MPs are commonly found in the operating room, and pre- and post-operative settings, and can trigger responses as severe as anaphylaxis. In this review, authors discuss the epidemiology, diagnosis and treatment of AGS reactions. Additionally, strategies are explored in order to screen and prevent exposure to MP with a multidisciplinary approach. While this emerging allergy is still not fully understood, it is of paramount importance that all anesthesia providers recognize the implications of MP exposure in AGS patients and ultimately prevent harm in this highly vulnerable population.

Indexed as

AnaphylaxisFood HypersensitivityAnimalsGalactoseHumansMammalsMeatGalactoseAlpha gal syndromeAnesthesiaHeparinMammalian productsRed meat allergySurgery

Identifiers

PMID36682226
PMCPMC11087933
OpenAlexW4317566686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.