Evidence map›Paper›PMID 36682182›Full record

ArticleBehaviour research and therapy2023

An examination of bidirectional associations between physical activity and mood symptoms among individuals diagnosed and at risk for bipolar spectrum disorders.

Rachel F L Walsh, Logan T Smith, Joshua Klugman, Madison K Titone, Tommy H Ng, Namni Goel, Lauren B Alloy

Abstract read
In one paragraph

Article in Behaviour research and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachel F L WalshDepartment of Psychology and Neuroscience, Temple University, USA.
Logan T SmithDepartment of Psychology and Neuroscience, Temple University, USA.
Joshua KlugmanDepartment of Psychology and Neuroscience, Temple University, USA; Department of Sociology, Temple University, USA.
Madison K TitoneVA San Diego Healthcare System, USA; University of California San Diego, USA.
Tommy H NgDepartment of Psychiatry, Weill Cornell Medicine College, USA.
Namni GoelDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, USA.
Lauren B AlloyDepartment of Psychology and Neuroscience, Temple University, USA. Electronic address: lalloy@temple.edu.

Funding

Risk for Bipolar Disorder: Reward-related Brain Function & Social RhythmsR01MH077908 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2007 to 2017
$5.7M
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in Adolescence SupplementR01MH126911 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH, NUSSLOCK, ROBIN · 2021 to 2025
$3.8M
Impact of Daytime vs. Delayed Eating Schedule on Weight and Metabolic Markers Among Obese Persons: An Examination of Circadian MechanismsR01DK117488 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI ALLISON, KELLY C, GOEL, NAMNI · 2017 to 2021
$3.8M
Social and Circadian Rhythms, Reward Sensitivity, and Risk for Bipolar DisorderR01MH102310 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2014 to 2017
$1.6M
NIDDK NIH HHS R01 DK117488NIMH NIH HHS R01 MH077908NIMH NIH HHS R01 MH102310NIMH NIH HHS R01 MH126911
6 · The paper itself

Abstract

objectivesActivation, a construct including energy and activity, is a central feature of Bipolar Spectrum Disorders (BSDs). Prior research found motor activity is associated with affect, and this relationship may be stronger for individuals with BSDs. The aims of this study were to investigate bidirectional relationships between physical activity and mood and evaluate whether bipolar risk status moderated potential associations.

methodsYoung adults at low-risk, high-risk, and diagnosed with BSD participated in a 20-day EMA study in which they wore an actiwatch to measure physical activity and sleep/wake cycles. They also reported depressive and hypo/manic symptoms three times daily. Multilevel linear models were estimated to examine how bipolar risk group moderated bidirectional relationships between physical activity and mood symptoms at within-day and between-day timescales.

resultsPhysical activity was significantly associated with subsequent mood symptoms at the within-day level. The relationship between physical activity and depressive symptoms was moderated by BSD risk group. An increase in physical activity resulted in a greater reduction of depressive symptoms for the BSD group compared to the low-risk and high-risk groups.

conclusionsInterventions targeting activity like behavioral activation may improve residual inter-episode mood symptoms.

Indexed as

Bipolar DisorderAffectExerciseHumansYoung AdultActigraphyBipolar spectrum disordersDepressive symptomsEcological momentary assessmentHypomanic symptomsPhysical activity

Identifiers

PMID36682182
PMCPMC9909602

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.