Evidence map›Paper›PMID 36682154›Full record

ArticleMedical image analysis2023

Deep learning prediction of diffusion MRI data with microstructure-sensitive loss functions.

Geng Chen, Yoonmi Hong, Khoi Minh Huynh, Pew-Thian Yap

Abstract read
In one paragraph

Article in Medical image analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. DIMOND: DIffusion Model OptimizatioN with Deep Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Diffusion MRI with Machine Learning.Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Geng ChenDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA; Biomedical Research Imaging Center (BRIC), University of North Carolina, Chapel Hill, NC, USA.
Yoonmi HongDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA; Biomedical Research Imaging Center (BRIC), University of North Carolina, Chapel Hill, NC, USA.
Khoi Minh HuynhDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA; Biomedical Research Imaging Center (BRIC), University of North Carolina, Chapel Hill, NC, USA.
Pew-Thian YapDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA; Biomedical Research Imaging Center (BRIC), University of North Carolina, Chapel Hill, NC, USA. Electronic address: ptyap@med.unc.edu.

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
Computational Diffusion MRI for Studying Early Human Brain DevelopmentR01MH125479 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2021 to 2025
$2.1M
Comprehensive MR Fingerprinting for Infants and Young Children at Risk for Developmental Delays.R01HD112923 · NICHD · DUKE UNIVERSITY · PI Dan Ma, DEANNE E WILSON-COSTELLO · 2024 to 2026
$1.7M
NIBIB NIH HHS R01 EB006733NIBIB NIH HHS R01 EB008374NICHD NIH HHS R01 HD112923NIMH NIH HHS R01 MH125479
6 · The paper itself

Abstract

Deep learning prediction of diffusion MRI (DMRI) data relies on the utilization of effective loss functions. Existing losses typically measure the signal-wise differences between the predicted and target DMRI data without considering the quality of derived diffusion scalars that are eventually utilized for quantification of tissue microstructure. Here, we propose two novel loss functions, called microstructural loss and spherical variance loss, to explicitly consider the quality of both the predicted DMRI data and derived diffusion scalars. We apply these loss functions to the prediction of multi-shell data and enhancement of angular resolution. Evaluation based on infant and adult DMRI data indicates that both microstructural loss and spherical variance loss improve the quality of derived diffusion scalars.

Indexed as

Deep LearningImage Processing, Computer-AssistedBrainDiffusionDiffusion Magnetic Resonance ImagingHumansData predictionDeep learningDiffusion MRILoss functions

Identifiers

PMID36682154
PMCPMC9974781

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.