Evidence map›Paper›PMID 36682037›Full record

ReviewCellular and molecular life sciences : CMLS2023

Aquaporin-mediated dysregulation of cell migration in disease states.

Ian M Smith, Shohini Banerjee, Allison K Moses, Kimberly M Stroka

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Potassium-Rich, Gluten-Free Diets for Patients with Sjögren's Syndrome: A Mini-ReviewEndocrine, metabolic & immune disorders drug targets · 2026
    Review
  4. Aquaporin 5 expression regulates MDA-MB-231 spheroid multicellular invasion.American journal of physiology. Cell physiology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. The multifaceted role of aquaporins in physiological cell migration.American journal of physiology. Cell physiology · 2023
    Review
  9. Article
  10. Methods for studying mammalian aquaporin biology.Biology methods & protocols · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ian M SmithFischell Department of Bioengineering, University of Maryland, 3110 A. James Clark Hall, 8278 Paint Branch Drive, College Park, MD, 20742, USA.
Shohini BanerjeeFischell Department of Bioengineering, University of Maryland, 3110 A. James Clark Hall, 8278 Paint Branch Drive, College Park, MD, 20742, USA.
Allison K MosesFischell Department of Bioengineering, University of Maryland, 3110 A. James Clark Hall, 8278 Paint Branch Drive, College Park, MD, 20742, USA.
Kimberly M StrokaFischell Department of Bioengineering, University of Maryland, 3110 A. James Clark Hall, 8278 Paint Branch Drive, College Park, MD, 20742, USA. kstroka@umd.edu.ORCID http://orcid.org/0000-0003-3314-2067

Funding

Exploring mechanisms of aquaporin-mediated cell migrationR35GM142838 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI STROKA, KIMBERLY · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM142838NIGMS NIH HHS R35GM142838
6 · The paper itself

Abstract

Dysregulated cell migration and invasion are hallmarks of many disease states. This dysregulated migratory behavior is influenced by the changes in expression of aquaporins (AQPs) that occur during pathogenesis, including conditions such as cancer, endometriosis, and arthritis. The ubiquitous function of AQPs in migration of diseased cells makes them a crucial target for potential therapeutics; this possibility has led to extensive research into the specific mechanisms underlying AQP-mediated diseased cell migration. The functions of AQPs depend on a diverse set of variables including cell type, AQP isoform, disease state, cell microenvironments, and even the subcellular localization of AQPs. To consolidate the considerable work that has been conducted across these numerous variables, here we summarize and review the last decade's research covering the role of AQPs in the migration and invasion of cells in diseased states.

Indexed as

AquaporinsEndometriosisCell MovementFemaleHumansProtein IsoformsAquaporinsProtein IsoformsCancerCell signalingCell volumeEndometriosis

Identifiers

PMID36682037
PMCPMC10280779

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.