Evidence map›Paper›PMID 36681852›Full record

ArticleJournal of neuroengineering and rehabilitation2023

Cost-effectiveness analysis of overground robotic training versus conventional locomotor training in people with spinal cord injury.

Daniel Pinto, Allen W Heinemann, Shuo-Hsiu Chang, Susan Charlifue, Edelle C Field-Fote, Catherine L Furbish, Arun Jayaraman, Candace Tefertiller, Heather B Taylor, Dustin D French

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Characterizing the Effects of Adding Virtual and Augmented Reality in Robot-Assisted Training.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Daniel PintoDepartment of Physical Therapy, College of Health Sciences, Marquette University, Milwaukee, USA. d.pinto@marquette.edu.
Allen W HeinemannCenter for Rehabilitation Outcomes Research, Shirley Ryan AbilityLab, Chicago, USA.
Shuo-Hsiu ChangNeurorecovery Research Center, TIRR Memorial Hermann, Houston, USA.
Susan CharlifueCraig Hospital, Englewood, USA.
Edelle C Field-FoteSpinal Cord Injury, Shepherd Center, Atlanta, Georgia.
Catherine L FurbishShepherd Center, Atlanta, Georgia.
Arun JayaramanMax Näder Center for Rehabilitation Technologies and Outcomes Research and Outcomes Research, Shirley Ryan AbilityLab, Chicago, USA.
Candace TefertillerResearch and Evaluation, Craig Hospital, Englewood, USA.
Heather B TaylorSpinal Cord Injury and Disability Research, TIRR Memorial Hermann, Houston, USA.
Dustin D FrenchDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, USA.
Craig Hospital · USMemorial Hermann Institute for Rehabilitation and Research Foundation · USShepherd Center · USHealth Services Research & Development · USMarquette University · USNorthwestern University · USShirley Ryan AbilityLab · US

Funding

Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MILDA Renne SAUNDERS · 2011 to 2026
$10.0M
NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

backgroundFew, if any estimates of cost-effectiveness for locomotor training strategies following spinal cord injury (SCI) are available. The purpose of this study was to estimate the cost-effectiveness of locomotor training strategies following spinal cord injury (overground robotic locomotor training versus conventional locomotor training) by injury status (complete versus incomplete) using a practice-based cohort.

methodsA probabilistic cost-effectiveness analysis was conducted using a prospective, practice-based cohort from four participating Spinal Cord Injury Model System sites. Conventional locomotor training strategies (conventional training) were compared to overground robotic locomotor training (overground robotic training). Conventional locomotor training included treadmill-based training with body weight support, overground training, and stationary robotic systems. The outcome measures included the calculation of quality adjusted life years (QALYs) using the EQ-5D and therapy costs. We estimate cost-effectiveness using the incremental cost utility ratio and present results on the cost-effectiveness plane and on cost-effectiveness acceptability curves.

resultsParticipants in the prospective, practice-based cohort with complete EQ-5D data (n = 99) qualified for the analysis. Both conventional training and overground robotic training experienced an improvement in QALYs. Only people with incomplete SCI improved with conventional locomotor training, 0.045 (SD 0.28), and only people with complete SCI improved with overground robotic training, 0.097 (SD 0.20). Costs were lower for conventional training, $1758 (SD $1697) versus overground robotic training $3952 (SD $3989), and lower for those with incomplete versus complete injury. Conventional overground training was more effective and cost less than robotic therapy for people with incomplete SCI. Overground robotic training was more effective and cost more than conventional training for people with complete SCI. The incremental cost utility ratio for overground robotic training for people with complete spinal cord injury was $12,353/QALY.

conclusionsThe most cost-effective locomotor training strategy for people with SCI differed based on injury completeness. Conventional training was more cost-effective than overground robotic training for people with incomplete SCI. Overground robotic training was more cost-effective than conventional training for people with complete SCI. The effect estimates may be subject to limitations associated with small sample sizes and practice-based evidence methodology. These estimates provide a baseline for future research.

Indexed as

RoboticsRobotic Surgical ProceduresSpinal Cord InjuriesCost-Effectiveness AnalysisHumansProspective StudiesWalkingExoskeleton deviceGaitPhysical therapy modalitiesQuality-adjusted life yearsSpinal cord injuries

Identifiers

PMID36681852
PMCPMC9867867
OpenAlexW4317670240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.