Evidence map›Paper›PMID 36681758›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2023

Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[

Katina C Calakos, Ansel T Hillmer, Jon Mikael Anderson, Brittany LeVasseur, Stephen R Baldassarri, Gustavo A Angarita, David Matuskey, Michael Kapinos, Ming-Qiang Zheng, Yiyun Huang and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Katina C CalakosInterdepartmental Neuroscience Program, Yale University, New Haven, CT, USA.ORCID 0000-0002-3872-4210
Ansel T HillmerDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID 0000-0002-8105-1381
Jon Mikael AndersonDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Brittany LeVasseurDepartment of Psychiatry, Yale University, New Haven, CT, USA.
Stephen R BaldassarriDepartment of Internal Medicine, Section of Pulmonary, Critical Care Medicine, & Sleep Medicine, Yale University, New Haven, CT, USA.
Gustavo A AngaritaDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID 0000-0001-5568-9878
David MatuskeyDepartment of Psychiatry, Yale University, New Haven, CT, USA.ORCID 0000-0001-7508-6572
Michael KapinosYale PET Center, Yale University, New Haven, CT, USA.
Ming-Qiang ZhengDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Yiyun HuangDepartment of Radiology and Biomedical Imaging, Yale University, New Haven, CT, USA.
Kelly P CosgroveDepartment of Psychiatry, Yale University, New Haven, CT, USA. kelly.cosgrove@yale.edu.ORCID 0000-0003-1351-9576
Yale University · USYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Interdepartmental Neuroscience Program (INP)T32NS041228 · NINDS · YALE UNIVERSITY · PI Charles A Greer, Marina R Picciotto · 2001 to 2026
$12.0M
Imaging Molecular Mechanisms of Tobacco Smoking WithdrawalR01DA038832 · NIDA · YALE UNIVERSITY · PI COSGROVE, KELLY P. · 2016 to 2021
$3.6M
Understanding Factors that Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine ReceptorsK23DA045957 · NIDA · YALE UNIVERSITY · PI BALDASSARRI, STEPHEN · 2018 to 2022
$983k
Multimodal Neuroimaging of Alcohol Withdrawal: The Role of Glutamate in Neural ReorganizationK01AA024788 · NIAAA · YALE UNIVERSITY · PI HILLMER, ANSEL · 2017 to 2021
$894k
Imaging Genetics in Tobacco SmokersK02DA031750 · NIDA · YALE UNIVERSITY · PI COSGROVE, KELLY P. · 2012 to 2016
$634k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K01 AA024788NIDA NIH HHS K02 DA031750NIDA NIH HHS K23 DA045957NIDA NIH HHS R01 DA038832NINDS NIH HHS T32 NS041228
6 · The paper itself

Abstract

The cholinergic system is a critical mediator of cognition in animals. People who smoke cigarettes exhibit cognitive deficits, especially during quit attempts. Few studies jointly examine the cholinergic system and cognition in people while trying to quit smoking. We used positron emission tomography (PET) brain imaging with the β

Indexed as

AcetylcholineReceptors, NicotinicAcetylcholinesteraseAnimalsBenzamidesBrainBridged Bicyclo Compounds, HeterocyclicCholinergic AgentsCognitionFemaleMalePhysostigminePositron-Emission TomographySmokingAcetylcholineAcetylcholinesteraseBenzamidesBridged Bicyclo Compounds, HeterocyclicCholinergic AgentsfluoronorchloroepibatidinePhysostigmineReceptors, Nicotinic

Identifiers

PMID36681758
PMCPMC9938267
OpenAlexW4317660922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.