Evidence map›Paper›PMID 36681582›Full record

ArticleTransplantation proceedings2023

The Outcome of COVID-19 Infection on Kidney Transplantation Recipients in Southern Saudi Arabia: Single-Center Experience.

Hany M El Hennawy, Omar Safar, Adel Elatreisy, Abdullah S Al Faifi, Osama Shalkamy, Sara Abdullah Hadi, Mofareh Alqahtani, Sultan Ahmad Alkahtani, Faisal Saeed Alqahtani, Weam El Nazer and 11 more

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Article in Transplantation proceedings, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 2 countries.

Hany M El HennawySurgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia. Electronic address: hennawyhany@hotmail.com.
Omar SafarUrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Adel ElatreisyUrology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Abdullah S Al FaifiSurgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Osama ShalkamyUrology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Sara Abdullah HadiSurgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Mofareh AlqahtaniUrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Sultan Ahmad AlkahtaniPathology and Laboratory Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Faisal Saeed AlqahtaniAdult Infectious Diseases Section, Internal Medicine Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Weam El NazerNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Eisa Al AttaSurgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Asad Taha IbrahimAnesthesia Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Abdelaziz A AbdelazizNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Naveed MirzaNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Ahmed MahedyNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Nayana Mary TomAnesthesia Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Yahya AssiriNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Ali Al FageehNephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Galal ElgamalAnesthesia Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Ali Amer Al ShehriAdult Infectious Diseases Section, Internal Medicine Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Mohammad F ZaitounPharmacy Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, Saudi Arabia.
Armed Forces Hospital · SAAl-Azhar University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo report the incidence, risk factors, and outcome of severe COVID-19 disease in kidney transplant recipients attending a Saudi hospital at a single center in the Kingdom of Saudi Arabia.

methodsA retrospective chart-based cohort study involving all kidney transplant recipients tested for COVID-19 in the Armed Forces Hospital Southern Region, KSA.

resultsOf 532 kidney transplant recipients who reported to the center, from March 2020 to June 2022, 180 were tested for COVID-19. Of these recipients, 31 (17%) tested positive. Among the 31 positive recipients, 11 were treated at home, 15 were admitted to the noncritical isolation ward, and 5 were admitted to the intensive care unit (ICU). Older age (P = .0001), higher body mass index (P = .0001), and history of hypertension (P = .0023) were more frequent in the COVID-19-positive recipients. Admission to the ICU was more frequent in older recipients (P = .0322) with a history of ischemic heart disease (P = .06) and higher creatinine baseline (P = .08) presenting with dyspnea (P = .0174), and acute allograft dysfunction (P = .002). In the ICU group, 4 (80%) patients required hemodialysis, and 4 (80%) died.

conclusionsKidney transplant recipients with COVID-19 could have a higher risk for developing acute kidney injury, dialysis, and mortality than the general population. ICU admission and renal replacement therapy were more evident in older recipients with a history of ischemic heart disease, presenting with shortness of breath (P = .017) and a higher serum creatinine baseline. Acute allograft dysfunction was the independent predictor of mortality among patients admitted to the ICU.

Indexed as

COVID-19Kidney TransplantationMyocardial IschemiaAgedCohort StudiesHumansIntensive Care UnitsRetrospective StudiesSaudi ArabiaTransplant Recipients

Identifiers

PMID36681582
PMCPMC9826984
OpenAlexW4313825811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.