Evidence map›Paper›PMID 36681421›Full record

ArticleThe Journal of investigative dermatology2023

Inhibiting EGFR Signaling Holds Promise for Treating Palmoplantar Keratodermas.

Pierre A Coulombe, Amanda Orosco

Abstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Pierre A CoulombeDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA. Electronic address: coulombe@umich.edu.
Amanda OroscoDepartment of Cell & Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA; Training program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, Michigan, USA.

Funding

Cellular and Molecular Biology at MichiganT32GM145470 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI John Chadwick Brenner · 2022 to 2026
$4.1M
Role of keratin intermediate filaments in skin epithelial differentiation.R01AR079418 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COULOMBE, PIERRE · 2021 to 2025
$2.1M
NIAMS NIH HHS R01 AR079418NIGMS NIH HHS T32 GM145470
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Keratoderma, PalmoplantarErbB ReceptorsHumansKeratinsEGFR protein, humanErbB ReceptorsKeratins

Identifiers

PMID36681421
PMCPMC10166065

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.