Evidence map›Paper›PMID 36681019›Full record

SynthesisGeneral hospital psychiatry

Positive psychological well-being and clinical characteristics in IBS: A systematic review.

Elizabeth N Madva, Monika Sadlonova, Lauren E Harnedy, Regina M Longley, Hermioni L Amonoo, Emily H Feig, Rachel A Millstein, Juliana Zambrano, Alexandra Rojas Amaris, Jane Jurayj and 6 more

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Elizabeth N MadvaHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; Center for Neurointestinal Health, Gastroenterology, Massachusetts General Hospital, Boston, MA, United States of America. Electronic address: emadva@mgh.harvard.edu.
Monika SadlonovaHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; Department of Psychosomatic Medicine and Psychotherapy, University of Göttingen Medical Center, Germany.
Lauren E HarnedyDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Regina M LongleyDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Hermioni L AmonooHarvard Medical School, Boston, MA, United States of America; Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute and Department of Psychiatry, Brigham and Women's Hospitals, Boston, MA, United States of America.
Emily H FeigHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Rachel A MillsteinHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Juliana ZambranoHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Alexandra Rojas AmarisDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Jane JurayjDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Helen Burton MurrayHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America; Center for Neurointestinal Health, Gastroenterology, Massachusetts General Hospital, Boston, MA, United States of America.
Kyle StallerHarvard Medical School, Boston, MA, United States of America; Center for Neurointestinal Health, Gastroenterology, Massachusetts General Hospital, Boston, MA, United States of America.
Braden KuoHarvard Medical School, Boston, MA, United States of America; Center for Neurointestinal Health, Gastroenterology, Massachusetts General Hospital, Boston, MA, United States of America.
Laurie KeeferMount Sinai Hospital School of Medicine, Psychiatry and Gastroenterology, New York, NY, United States of America.
Jeff C HuffmanHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Christopher M CelanoHarvard Medical School, Boston, MA, United States of America; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States of America.
Harvard University · USMassachusetts General Hospital · USBrigham and Women's Hospital · USMount Sinai Hospital · US

Funding

New England Gastropareis Consortium: Neurobiology of GastroparesisU01DK112193 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Helen Burton Murray, Braden Kuo · 2016 to 2026
$4.8M
A novel behavioral intervention to promote adherence in heart failureR01HL155301 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI CELANO, CHRISTOPHER M · 2021 to 2025
$3.8M
Pragmatic collaborative care for cardiac inpatients with depression or anxietyR01HL133149 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HUFFMAN, JEFF C · 2017 to 2021
$3.8M
TRANSLUMBOSACRAL NEUROMODULATION THERAPY FOR FECAL INCONTINENCE: RANDOMIZED TRIALR01DK121003 · NIDDK · AUGUSTA UNIVERSITY · PI KUO, BRADEN, RAO, SATISH SC · 2019 to 2023
$2.6M
Fostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3M
A Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients.K08CA251654 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI AMONOO, HERMIONI L. · 2020 to 2024
$1.3M
A Biobehavioral Approach to Understand Problematic Avoidant/Restrictive Eating in Adults with Functional DyspepsiaK23DK131334 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BURTON MURRAY, HELEN · 2021 to 2025
$1.1M
The Role of Fiber in the Etiopathogenesis of Fecal IncontinenceK23DK120945 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI STALLER, KYLE · 2020 to 2024
$1.0M
Testing the feasibility and preliminary efficacy of a psychological and behavioral intervention to promote physical activity after weight loss surgeryK23HL148017 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI FEIG, EMILY · 2020 to 2025
$1000k
Testing the feasibility and preliminary efficacy of a multilevel intervention to promote physical activity among patients with metabolic syndromeK23HL135277 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI MILLSTEIN, RACHEL A. · 2017 to 2021
$834k
NCI NIH HHS K08 CA251654NHLBI NIH HHS K23 HL135277NHLBI NIH HHS K23 HL148017NHLBI NIH HHS R01 HL133149NHLBI NIH HHS R01 HL155301NIDDK NIH HHS K23 DK120945NIDDK NIH HHS K23 DK131334NIDDK NIH HHS R01 DK121003NIDDK NIH HHS U01 DK112193NIMH NIH HHS R25 MH094612
6 · The paper itself

Abstract

objectivePsychological factors (e.g., depression, anxiety) are known to contribute to the development and maintenance of irritable bowel syndrome (IBS). Less is known, however, about the role of positive psychological well-being (PPWB) in IBS. Accordingly, we completed a systematic review of the literature examining relationships between PPWB and clinical characteristics in IBS.

methodA systematic review using search terms related to PPWB and IBS from inception through July 28, 2022, was completed. Quality was assessed with the NIH Quality Assessment Tool. A narrative synthesis of findings, rather than meta-analysis, was completed due to study heterogeneity.

results22 articles with a total of 4285 participants with IBS met inclusion criteria. Individuals with IBS had lower levels of PPWB (e.g., resilience, positive affect, self-efficacy, emotion regulation) compared to healthy populations, which in turn was associated with reduced physical and mental health and health-related quality of life (HRQoL). Limited exploration of potential biological mechanisms underlying these relationships has been described.

conclusionsPPWB is diminished in individuals with IBS compared to other populations, and greater PPWB is linked to superior physical, psychological, and HRQoL outcomes. Interventions to increase PPWB may have the potential to improve IBS-related outcomes. REGISTRATION: Prospective Register of Systematic Reviews CRD42022304767.

Indexed as

Irritable Bowel SyndromeAnxietyHumansPsychological Well-BeingQuality of LifeFunctional gastrointestinal disordersIrritable bowel syndromePsychology, positivePsychosomatic medicine

Identifiers

PMID36681019
PMCPMC9992118
OpenAlexW4315488110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.