Evidence map›Paper›PMID 36680575›Full record

ArticleSocial psychiatry and psychiatric epidemiology2023

Military service and risk of subsequent drug use disorders among Swedish men.

Alexis C Edwards, Henrik Ohlsson, Peter B Barr, Jan Sundquist, Kenneth S Kendler, Kristina Sundquist

Open access · greenAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alexis C EdwardsDepartment of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Box 980126, RichmondRichmond, VA, 23298-0126, USA. alexis.edwards@vcuhealth.org.ORCID http://orcid.org/0000-0002-4006-9710
Henrik OhlssonCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Peter B BarrDepartment of Psychiatry and Behavioral Sciences, State University of New York-Downstate, Brooklyn, NY, USA.ORCID http://orcid.org/0000-0001-9321-657X
Jan SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0001-7228-5015
Kenneth S Kendler *Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine, Box 980126, RichmondRichmond, VA, 23298-0126, USA.ORCID http://orcid.org/0000-0001-8689-6570
Kristina Sundquist *Center for Primary Health Care Research, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0001-8031-279X
Lund University · SEVirginia Commonwealth University · USState University of New York · US

Funding

Genetic, Social, and Developmental Epidemiology of Drug Use DisordersR01DA030005 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENNETH SEEDMAN KENDLER, JAN O SUNDQUIST · 2010 to 2026
$7.6M
Social, Developmental and Genetic Epidemiology of Alcohol Use DisordersR01AA023534 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN, SUNDQUIST, KRISTINA · 2015 to 2023
$4.0M
The Etiology of Risk: Alcohol Use Disorder and Suicidal BehaviorR01AA027522 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Alexis C Edwards, Kristina Sundquist · 2019 to 2026
$3.5M
NIAAA NIH HHS AA023534NIAAA NIH HHS AA027522NIAAA NIH HHS R01 AA023534NIAAA NIH HHS R01 AA027522NIDA NIH HHS DA030005NIDA NIH HHS R01 DA030005
6 · The paper itself

Abstract

purposeEnvironmental factors contribute substantially to risk for drug use disorders (DUD). The current study applies multiple methods to empirically test whether military service is associated with subsequent DUD, as previous findings are inconsistent.

methodsLongitudinal Swedish national registry data on a cohort of male conscripts born 1972-1987 (maximum N = 485,900) were used to test the association between military service and subsequent registration for DUD. Cox proportional hazard models were used in preliminary analyses, followed by three methods that enable causal inference: propensity score models, co-relative models, and instrumental variable analysis.

resultsAcross all methods, military service was causally associated with lower risk of DUD. Hazard ratios ranged from HR = 0.43 (95% confidence intervals [CI] 0.37; 0.50) in the instrumental variable analysis to 0.77 (0.75; 0.79) in the multivariate propensity score matching analysis. This effect diminished across time. In the model including a propensity score, HRs remained below 1 across the observation period, while confidence intervals included 1 after ~ 11 years in the co-relative analysis and after ~ 21 years in the instrumental variable analysis.

conclusionsIn this cohort of Swedish men, complementary methods indicate that military service conferred substantial but time-limited protection against subsequent DUD. The observed effect could be due to reduced opportunity for substance use during service, social cohesion experienced during and after service, and/or socioeconomic advantages among veterans. Additional research is necessary to clarify these protective mechanisms and determine how other environmental contexts can provide similar benefits.

Indexed as

Military PersonnelSubstance-Related DisordersVeteransHumansMaleSwedenDrug use disorderInstrumental variableMilitary serviceRegistry data

Identifiers

PMID36680575
PMCPMC10916707
OpenAlexW4317659811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.