Evidence map›Paper›PMID 36680446›Full record

ArticleAnatolian journal of cardiology2023

The Prognostic Impact of Pericardial Fluid Cytology in Malignant Pericardial Effusion.

Burak Sezenöz, Feriha Pınar Uyar Göçün, Emrullah Kızıltunç, Salih Topal, Hüseyin Murat Özdemir

Open access · diamondAbstract read
In one paragraph

Article in Anatolian journal of cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Burak SezenözDepartment of Cardiology, Faculty of Medicine, Gazi University, Ankara, Türkiye.
Feriha Pınar Uyar GöçünDepartment of Pathology, Faculty of Medicine, Gazi University, Ankara, Türkiye.
Emrullah KızıltunçDepartment of Cardiology, Faculty of Medicine, Gazi University, Ankara, Türkiye.
Salih TopalDepartment of Cardiology, Faculty of Medicine, Gazi University, Ankara, Türkiye.
Hüseyin Murat ÖzdemirDepartment of Cardiology, Faculty of Medicine, Gazi University, Ankara, Türkiye.
Gazi University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMalignant pericardial effusion may affect almost 15 of the patients with underlying malignancies which deteriorates the prognosis. The prognostic significance of pericardial fluid cytology is under-represented in previous studies.

methodsA total of 73 patients with symptomatic pericardial effusion treated with pericardiocentesis were included in this retrospective analysis. Macroscopic appearance, biochemical features, and cytological findings were obtained. Patients were divided into 3 groups: (i) without malignancy, (ii) with malignancy and negative cytology, and (iii) with malignancy and positive cytology. Survival data were searched via governmental death notification system.

resultsMean age of the study group was 62 ± 15, and 54% (40) of the patients were female. On the cytological evaluation, 17 patients (23.3%) revealed positive cancer cytology, whereas 56 patients (76.7%) revealed negative cancer cytology. The median follow-up period was 840 days, and 34 patients (46.5%) died during follow-up. The survival rate of Group 3 was found to be significantly worse compared to Groups 1 and 2, no statistical difference was found between Groups 1 and 2 in terms of survival (Group 1 vs. Group 2 P =.078; Group 1 vs. Group 3 P <.001; Group 2 vs. Group 3 P =.041).

conclusionCytological evaluation is an important step in patients with malignant pericardial effusion. Positive pericardial fluid cytology indicates a poorer prognosis.

Indexed as

Heart NeoplasmsPericardial EffusionFemaleHumansMalePericardial FluidPrognosisRetrospective Studies

Identifiers

PMID36680446
PMCPMC9893710
OpenAlexW4317503975

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.