Evidence map›Paper›PMID 36680241›Full record

ArticleViruses2023

Seroprevalence of Natural and Acquired Immunity against the SARS-CoV-2 Virus in a Population Cohort from Two Chilean Cities, 2020-2022.

Loreto Núñez-Franz, Muriel Ramírez-Santana, Paola Rubilar, Cecilia Vial, Mauricio Apablaza, Claudia González, Macarena Said, Kathya Olivares, Lina Jimena Cortés, Juan Hormazábal and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Loreto Núñez-FranzDepartamento de Salud Pública, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile.
Muriel Ramírez-SantanaPublic Health Department, Faculty of Medicine, Universidad Católica del Norte, Coquimbo 1780000, Chile.ORCID 0000-0002-3642-6965
Paola RubilarCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 7550000, Chile.ORCID 0000-0003-3578-459X
Cecilia VialInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 8320000, Chile.ORCID 0000-0002-0399-6144
Mauricio ApablazaFacultad de Gobierno, Universidad del Desarrollo, Santiago 7550000, Chile.
Claudia GonzálezCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 7550000, Chile.
Macarena SaidDepartamento de Salud Pública, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Chile.
Kathya OlivaresPublic Health Department, Faculty of Medicine, Universidad Católica del Norte, Coquimbo 1780000, Chile.
Lina Jimena CortésInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 8320000, Chile.ORCID 0000-0001-8119-5417
Juan HormazábalInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 8320000, Chile.ORCID 0000-0003-0726-2778
Luis CanalesFacultad de Economía y Negocios, Universidad de Talca, Talca 3460000, Chile.ORCID 0000-0002-7518-4778
Pablo VialInstituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 8320000, Chile.
Gloria IcazaFacultad de Economía y Negocios, Universidad de Talca, Talca 3460000, Chile.
Rubén Quezada-GaetePublic Health Department, Faculty of Medicine, Universidad Católica del Norte, Coquimbo 1780000, Chile.
Ximena AguileraCentro de Epidemiología y Políticas de Salud, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago 7550000, Chile.ORCID 0000-0002-8153-6733
Universidad del Desarrollo · CLUniversity of Talca · CLUniversidad Católica del Norte · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChile has achieved the highest coverage for vaccines against the SARS-CoV-2 virus worldwide.

objectiveTo assess the progression of immunity (natural and acquired by vaccine) in a cohort from two Chilean cities.

methodsIndividuals (

resultsSeroprevalence was 3.6% in the first round and increased to 96.9% in the second and 98.7% in the third. In the third round, 75% of individuals who had received the basal full scheme were seropositive at 180 days or more since their last dose; 98% of individuals who received one booster dose were seropositive at 180 days or more, and 100% participants who received two boosters were seropositive, regardless of time since their last dose. Participants receiving mRNA vaccines had higher seroprevalence rates over time.

conclusionsThe high vaccination coverage in Chile enabled the population to maintain high levels of antibodies. Vaccination boosters are essential to maintain immunity over time, which also depends on the type of vaccine administered.

Indexed as

COVID-19SARS-CoV-2Adaptive ImmunityAntibodies, ViralChileCitiesHumansSeroepidemiologic StudiesAntibodies, ViralantibodiesChileCOVID-19immunityseroepidemiologyseroprevalencevaccines

Identifiers

PMID36680241
PMCPMC9861850
OpenAlexW4315649046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.