Evidence map›Paper›PMID 36680174›Full record

ArticleViruses2022

Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies.

Wenting Jiang, Dawei Jiang, Lu Li, Jiabin Wang, Panpan Wang, Xuejian Shi, Qi Zhao, Boyuan Liu, Pengchao Ji, Gaiping Zhang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Wenting JiangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Dawei JiangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Lu LiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Jiabin WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Panpan WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Xuejian ShiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Qi ZhaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Boyuan LiuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Pengchao JiCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Gaiping ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Henan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

African swine fever virus (ASFV) is a highly infectious viral pathogen that endangers the global pig industry, and no effective vaccine is available thus far. The CD2v protein is a glycoprotein on the outer envelope of ASFV, which mediates the transmission of the virus in the blood and recognition of the virus serotype, playing an important role in ASFV vaccine development and disease prevention. Here, we generated two specific monoclonal antibodies (mAbs), 6C11 and 8F12 (subtype IgG1/kappa-type), against the ASFV CD2v extracellular domain (CD2v-ex, GenBank: MK128995.1, 1-588 bp) and characterized their specificity. Peptide scanning technology was used to identify the epitopes recognized by mAbs 6C11 and 8F12. As a result, two novel B cell epitopes,

Indexed as

African Swine FeverAfrican Swine Fever VirusAnimalsAntibodies, MonoclonalEpitopes, B-LymphocyteSwineViral ProteinsAntibodies, MonoclonalEpitopes, B-LymphocyteViral ProteinsAfrican swine fever virusB cell epitopeCD2videntificationmonoclonal antibody

Identifiers

PMID36680174
PMCPMC9866794
OpenAlexW4313471432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.