Evidence map›Paper›PMID 36680143›Full record

Observational studyViruses2022

Effectiveness of Sotrovimab in the Omicron Storm Time: A Case Series.

Gaetano Cicchitto, Lorena Cardillo, Davide Sequino, Paola Sabatini, Luisa Adamo, Rosita Marchitiello, Maurizio Viscardi, Loredana Cozzolino, Antonietta Cavallera, Marialuisa Bocchino and 5 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Gaetano CicchittoCOVID-19 Hospital "M. Scarlato", Department of Pneumology, 84018 Salerno, Italy.
Lorena CardilloIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.ORCID 0000-0003-3050-1095
Davide SequinoDepartment of Clinical Medicine and Surgery, Section of Respiratory Disease Federico II University Hospital, 80055 Naples, Italy.ORCID 0000-0002-8718-5989
Paola SabatiniUmberto I" Hospital, Unit of Virology and Microbiology, Nocera Inferiore, 84018 Salerno, Italy.
Luisa AdamoUmberto I" Hospital, Unit of Virology and Microbiology, Nocera Inferiore, 84018 Salerno, Italy.
Rosita MarchitielloCOVID-19 Hospital "M. Scarlato", Unit of Clinical Pathology Laboratory, 84018 Salerno, Italy.
Maurizio ViscardiIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.
Loredana CozzolinoIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.
Antonietta CavalleraCOVID-19 Hospital "M. Scarlato", Department of Radiology, 84018 Salerno, Italy.
Marialuisa BocchinoDepartment of Clinical Medicine and Surgery, Section of Respiratory Disease Federico II University Hospital, 80055 Naples, Italy.
Alessandro Sanduzzi ZamparelliDepartment of Clinical Medicine and Surgery, Section of Respiratory Disease Federico II University Hospital, 80055 Naples, Italy.ORCID 0000-0002-0977-2643
Francesco FerrignoCOVID-19 Hospital "M. Scarlato", Department of Pneumology, 84018 Salerno, Italy.
Esterina de CarloIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.ORCID 0000-0001-7883-1283
Claudio de MartinisIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.ORCID 0000-0002-0948-5513
Giovanna FuscoIstituto Zooprofilattico Sperimentale del Mezzogiorno, Via Salute 2, 80055 Naples, Italy.ORCID 0000-0003-3139-7672
Istituto Zooprofilattico Sperimentale del Mezzogiorno · ITFederico II University Hospital · ITPoliclinico Umberto I · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutralizing monoclonal antibodies (mAbs) for pre- and post-exposure prophylaxis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are largely used to prevent the progression of the disease by blocking viral attachment, host cell entry, and infectivity. Sotrovimab, like other available mAbs, has been developed against the receptor binding Domain of the

Indexed as

Antibodies, Monoclonal, HumanizedAntibodies, NeutralizingCOVID-19Antibodies, ViralHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, Monoclonal, HumanizedAntibodies, NeutralizingAntibodies, ViralsotrovimabSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2chronic kidney diseaseimmune suppressionmonoclonal antibody treatmentOmicron variantSARS-CoV-2sotrovimabvariant of concern

Identifiers

PMID36680143
PMCPMC9864548
OpenAlexW4313316936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.