Evidence map›Paper›PMID 36679957›Full record

ReviewVaccines2023

Risks of Cardiac Arrhythmia Associated with COVID-19 Vaccination: A Systematic Review and Meta-Analysis.

Mohammed H Abutaleb, Hafiz A Makeen, Abdulkarim M Meraya, Saad S Alqahtani, Bayan Ibrahim Al-Mass, Reaam Omar Aljazaeri, Bushra Dhuhayyan Alhazmi, Afnan Mohammed Noor Kalakattawi, Ahmed Ali Alajam

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Potential Mechanisms of Arrhythmia in Coronavirus disease-2019.International journal of medical sciences · 2024
    Review
  7. Article
  8. Article
  9. Arrhythmias after COVID-19 Vaccination: Have We Left All Stones Unturned?International journal of molecular sciences · 2023
    Review
  10. COVID-19 HEART unveiling as atrial fibrillation: pathophysiology, management and future directions for research.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Mohammed H AbutalebPharmaceutical Care Department, King Fahad Central Hospital, Jazan Health Affairs, Ministry of Health, Jazan 82912, Saudi Arabia.ORCID 0000-0002-5300-5900
Hafiz A MakeenPharmacy Practice Research Unit, Department of Pharmacy Practice, College of Pharmacy, Jazan University, Jazan 82912, Saudi Arabia.ORCID 0000-0002-1078-2478
Abdulkarim M MerayaPharmacy Practice Research Unit, Department of Pharmacy Practice, College of Pharmacy, Jazan University, Jazan 82912, Saudi Arabia.
Saad S AlqahtaniPharmacy Practice Research Unit, Department of Pharmacy Practice, College of Pharmacy, Jazan University, Jazan 82912, Saudi Arabia.ORCID 0000-0002-6164-9095
Bayan Ibrahim Al-MassCollege of Clinical Pharmacy, King Faisal University, Alahsa 31982, Saudi Arabia.
Reaam Omar AljazaeriCollege of Pharmacy, Aljouf University, Sakaka 72311, Saudi Arabia.
Bushra Dhuhayyan AlhazmiCollege of Clinical Pharmacy, Northern Border University, Arar 91431, Saudi Arabia.
Afnan Mohammed Noor KalakattawiCollege of Clinical Pharmacy, Taif University, Taif 21974, Saudi Arabia.
Ahmed Ali AlajamPharmaceutical Care Department, Aldarb General Hospital, Jazan 89876, Saudi Arabia.
Jazan University · SAJouf University · SAKing Fahad Central Hospital · SAKing Faisal University · SANorthern Border University · SATaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis aimed to summarize the current evidence regarding the association between coronavirus disease 2019 (COVID-19) vaccination and the risk of cardiac arrhythmia. MEDLINE, via PubMed and OVID, Scopus, CENTRAL, and Web of Science were searched using the relevant keywords to identify the relevant citations. Comprehensive Meta-analysis and Review Manager 5.4.1 were used for all the statistical analyses. Seventeen studies (n = 567,033,087 patients) were included. The pooled analysis showed that the incidence of cardiac arrhythmia post-COVID-19 vaccination with Pfizer, Moderna, AstraZeneca, CoronaVac, and Sinopharm was 0.22%, 95% CI: (0.07% to 0.66%), 0.76%, 95% CI: (0.04% to 12.08%), 0.04%, 95% CI: (0.00% to 0.98%), 0.01%, 95% CI: (0.00% to 0.03%), and 0.03%, 95% CI: (0.00% to 18.48%), respectively. Compared to CoronaVac, Pfizer, Moderna, AstraZeneca, and Sinopharm had a higher incidence ratio rate (IRR; 22-times, 76-times, 4-times, and 3-times higher), respectively. Likewise, Pfizer, Moderna, and AstraZeneca showed a higher IRR than Sinopharm (7.3-times, 25.3-times, and 1.3-times higher). The current evidence shows that the incidence rate (IR) of cardiac arrhythmia post-COVID-19 vaccination is rare and ranges between 1 and 76 per 10,000. mRNA vaccines were associated with a higher IR of arrhythmia compared to vector-based vaccines. Inactivated vaccines showed the lowest IR of arrhythmia.

Indexed as

arrhythmiaCOVID-19incidencemeta-analysisvaccine

Identifiers

PMID36679957
PMCPMC9862670
OpenAlexW4313519313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.