Evidence map›Paper›PMID 36679755›Full record

ArticleSensors (Basel, Switzerland)2023

The Actigraphy-Based Identification of Premorbid Latent Liability of Schizophrenia and Bipolar Disorder.

Ádám Nagy, József Dombi, Martin Patrik Fülep, Emese Rudics, Emőke Adrienn Hompoth, Zoltán Szabó, András Dér, András Búzás, Zsolt János Viharos, Anh Tuan Hoang and 6 more

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. [Risk Prediction Performance of Blood Biomarkers for Bipolar Disorder With Psychotic Symptoms].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ádám NagyDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0003-3321-004X
József DombiDepartment of Computer Algorithms and Artificial Intelligence, University of Szeged, 2 Árpád Square, 6720 Szeged, Hungary.ORCID 0000-0001-9459-912X
Martin Patrik FülepDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0001-6946-5795
Emese RudicsDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0001-7108-9530
Emőke Adrienn HompothDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0002-7085-3901
Zoltán SzabóDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0003-3863-7595
András DérELKH Biological Research Centre, Institute of Biophysics, 62 Temesvári Boulevard, 6726 Szeged, Hungary.ORCID 0000-0001-6112-884X
András BúzásELKH Biological Research Centre, Institute of Biophysics, 62 Temesvári Boulevard, 6726 Szeged, Hungary.ORCID 0000-0001-7318-4232
Zsolt János ViharosInstitute for Computer Science and Control, Center of Excellence in Production Informatics and Control, Eötvös Lóránd Research Network (ELKH), Center of Excellence of the Hungarian Academy of Sciences (MTA), 13-17 Kende Street, 1111 Budapest, Hungary.ORCID 0000-0002-9561-6857
Anh Tuan HoangInstitute for Computer Science and Control, Center of Excellence in Production Informatics and Control, Eötvös Lóránd Research Network (ELKH), Center of Excellence of the Hungarian Academy of Sciences (MTA), 13-17 Kende Street, 1111 Budapest, Hungary.ORCID 0000-0003-4316-0373
Bálint MaczákDepartment of Technical Informatics, University of Szeged, 2 Árpád Square, 6720 Szeged, Hungary.ORCID 0000-0002-1867-5861
Gergely VadaiDepartment of Technical Informatics, University of Szeged, 2 Árpád Square, 6720 Szeged, Hungary.ORCID 0000-0002-2720-3380
Zoltán GinglDepartment of Technical Informatics, University of Szeged, 2 Árpád Square, 6720 Szeged, Hungary.ORCID 0000-0001-6570-2685
Szandra LászlóDoctoral School of Interdisciplinary Medicine, Department of Medical Genetics, University of Szeged, 4 Somogyi Béla Street, 6720 Szeged, Hungary.
Vilmos BilickiDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0002-7793-2661
István SzendiDepartment of Software Engineering, University of Szeged, 13 Dugonics Square, 6720 Szeged, Hungary.ORCID 0000-0002-2612-7291

Funding

European Union GINOP-2.3.2-15-2016-00037
6 · The paper itself

Abstract

(1) Background and Goal: Several studies have investigated the association of sleep, diurnal patterns, and circadian rhythms with the presence and with the risk states of mental illnesses such as schizophrenia and bipolar disorder. The goal of our study was to examine actigraphic measures to identify features that can be extracted from them so that a machine learning model can detect premorbid latent liabilities for schizotypy and bipolarity. (2) Methods: Our team developed a small wrist-worn measurement device that collects and identifies actigraphic data based on an accelerometer. The sensors were used by carefully selected healthy participants who were divided into three groups: Control Group (C), Cyclothymia Factor Group (CFG), and Positive Schizotypy Factor Group (PSF). From the data they collected, our team performed data cleaning operations and then used the extracted metrics to generate the feature combinations deemed most effective, along with three machine learning algorithms for categorization. (3) Results: By conducting the training, we were able to identify a set of mildly correlated traits and their order of importance based on the Shapley value that had the greatest impact on the detection of bipolarity and schizotypy according to the logistic regression, Light Gradient Boost, and Random Forest algorithms. (4) Conclusions: These results were successfully compared to the results of other researchers; we had a similar differentiation in features used by others, and successfully developed new ones that might be a good complement for further research. In the future, identifying these traits may help us identify people at risk from mental disorders early in a cost-effective, automated way.

Indexed as

Bipolar DisorderSchizophreniaActigraphyCircadian RhythmHumansSleepactigraphybipolar disorderlight gradient boostlinear regressionmachine learningrandom forestschizophrenia

Identifiers

PMID36679755
PMCPMC9863012

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.