Evidence map›Paper›PMID 36679249›Full record

ArticlePolymers2023

Sterilization of PLA after Fused Filament Fabrication 3D Printing: Evaluation on Inherent Sterility and the Impossibility of Autoclavation.

Jonas Neijhoft, Dirk Henrich, Andreas Kammerer, Maren Janko, Johannes Frank, Ingo Marzi

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  7. Review
  8. Article
  9. Evaluation of a 3D-printed hands-on radius fracture model during teaching courses.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jonas NeijhoftDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.ORCID 0000-0003-2040-0100
Dirk HenrichDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.ORCID 0000-0002-9728-4032
Andreas KammererDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.
Maren JankoDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.
Johannes FrankDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.
Ingo MarziDepartment of Trauma, Hand and Reconstructive Surgery, Goethe University Frankfurt, University Hospital, 60326 Frankfurt, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional printing, especially fused filament fabrication (FFF), offers great possibilities in (bio-)medical applications, but a major downside is the difficulty in sterilizing the produced parts. This study evaluates the questions of whether autoclaving is a possible solution for FFF-printed parts and if the printer itself could be seen as an inherent sterilization method. In a first step, an investigation was performed on the deformation of cylindrically shaped test parts after running them through the autoclaving process. Furthermore, the inherent sterility possibilities of the printing process itself were evaluated using culture medium sterility tests. It could be shown that, depending on the needed accuracy, parts down to a diameter of 5-10 mm can still be sterilized using autoclaving, while finer parts suffer from major deformations. For these, inherent sterilization of the printer itself is an option. During the printing process, over a certain contact time, heat at a higher level than that used in autoclaving is applied to the printed parts. The contact time, depending on the printing parameters, is calculated using the established formula. The results show that for stronger parts, autoclaving offers a cheap and good option for sterilization after FFF-printing. However, the inherent sterility possibilities of the printer itself can be considered, especially when printing with small layer heights for finer parts.

Indexed as

3D printingautoclavingfused filament fabricationpolylactic acidsterilizationthermal deformationtraumatology

Identifiers

PMID36679249
PMCPMC9866509
OpenAlexW4315648180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.