Evidence map›Paper›PMID 36679069›Full record

ArticlePlants (Basel, Switzerland)2023

Study of the Chemical Profile and Anti-Fungal Activity against

Roberto Rosato, Edoardo Napoli, Giuseppe Granata, Maura Di Vito, Stefania Garzoli, Corrada Geraci, Silvia Rizzo, Riccardo Torelli, Maurizio Sanguinetti, Francesca Bugli

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Antifungal and biodegradable nanoencapsulation ofFrontiers in microbiology · 2025
    Article
  5. Article
  6. Essential Oils againstAntibiotics (Basel, Switzerland) · 2024
    Review
  7. Current Perspectives of Antifungal Therapy: A Special Focus onJournal of fungi (Basel, Switzerland) · 2024
    Review
  8. Article
  9. An Overview onJournal of fungi (Basel, Switzerland) · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roberto RosatoDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, 00167 Rome, Italy.
Edoardo NapoliIstituto di Chimica Biomolecolare-Consiglio Nazionale delle Ricerche, 95126 Catania, Italy.ORCID 0000-0003-4281-3256
Giuseppe GranataIstituto di Chimica Biomolecolare-Consiglio Nazionale delle Ricerche, 95126 Catania, Italy.ORCID 0000-0001-9428-3985
Maura Di VitoDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, 00167 Rome, Italy.ORCID 0000-0002-2991-0855
Stefania GarzoliDipartimento di Chimica e Tecnologie del Farmaco, Università di Roma Sapienza, Piazzale Aldo Moro 5, 00100 Rome, Italy.ORCID 0000-0001-8535-0533
Corrada GeraciIstituto di Chimica Biomolecolare-Consiglio Nazionale delle Ricerche, 95126 Catania, Italy.ORCID 0000-0001-5850-0372
Silvia RizzoDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, 00167 Rome, Italy.
Riccardo TorelliDipartimento di Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.
Maurizio SanguinettiDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, 00167 Rome, Italy.ORCID 0000-0002-9780-7059
Francesca BugliDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie, Università Cattolica del Sacro Cuore, 00167 Rome, Italy.ORCID 0000-0001-9038-3233

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsnanoparticles of PCL were produced using CC-EO (nano-CC-EO) and cinnamaldehyde (CIN) through the nanoprecipitation method. The chemical profile of both CC-EO and nano-CC-EO was evaluated using SPME sampling followed by GC-MS analysis. Micro-broth dilution tests were performed to evaluate both fungistatic and fungicidal effectiveness of CC-EO and CIN, pure and nano-formulated. Furthermore, checkerboard tests to evaluate the synergistic action of CC-EO or nano-CC-EO with micafungin or fluconazole were conducted. Finally, the biofilm disrupting activity of both formulations was evaluated.

resultsGC-MS analysis shows a different composition between CC-EO and nano-CC-EO. Moreover, the microbiological analyses do not show any variation in antifungal effectiveness either towards the planktonic form (MIC

conclusionsboth CC-EO and nano-CC-EO show the same antimicrobial effectiveness and are potential assets in the fight against

Indexed as

antifungal propertiescinnamaldehydecinnamon

Identifiers

PMID36679069
PMCPMC9860731

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.