Evidence map›Paper›PMID 36678899›Full record

ReviewPharmaceutics2023

Natural Compounds and Biopolymers-Based Hydrogels Join Forces to Promote Wound Healing.

Federica Falbo, Umile Gianfranco Spizzirri, Donatella Restuccia, Francesca Aiello

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Shikonin and CoFrontiers in chemistry · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Gelatin/hyaluronic acid-basedRegenerative biomaterials · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Federica FalboDepartment of Pharmacy, Health, and Nutritional Sciences, University of Calabria, Edificio Poli-Funzionale, 87036 Rende, CS, Italy.
Umile Gianfranco SpizzirriDepartment of Pharmacy, Health, and Nutritional Sciences, University of Calabria, Edificio Poli-Funzionale, 87036 Rende, CS, Italy.ORCID 0000-0002-5447-9497
Donatella RestucciaDepartment of Pharmacy, Health, and Nutritional Sciences, University of Calabria, Edificio Poli-Funzionale, 87036 Rende, CS, Italy.ORCID 0000-0002-3415-3828
Francesca AielloDepartment of Pharmacy, Health, and Nutritional Sciences, University of Calabria, Edificio Poli-Funzionale, 87036 Rende, CS, Italy.ORCID 0000-0001-6846-5582
University of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid and complete wound healing is a clinical emergency, mainly in pathological conditions such as Type 2 Diabetes mellitus. Many therapeutic tools are not resolutive, and the research for a more efficient remedial remains a challenge. Wound dressings play an essential role in diabetic wound healing. In particular, biocompatible hydrogels represent the most attractive wound dressings due to their ability to retain moisture as well as ability to act as a barrier against bacteria. In the last years, different functionalized hydrogels have been proposed as wound dressing materials, showing encouraging outcomes with great benefits in the healing of the diabetic wounds. Specifically, because of their excellent biocompatibility and biodegradability, natural bioactive compounds, as well as biomacromolecules such as polysaccharides and protein, are usually employed in the biomedical field. In this review, readers can find the main discoveries regarding the employment of naturally occurring compounds and biopolymers as wound healing promoters with antibacterial activity. The emerging approaches and engineered devices for effective wound care in diabetic patients are reported and deeply investigated.

Indexed as

antibacterial activitybiopolymerspolyphenolswound healing

Identifiers

PMID36678899
PMCPMC9863749
OpenAlexW4316039937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.