ArticlePharmaceutics2023
ZnO@ZIF-8 Nanoparticles as Nanocarrier of Ciprofloxacin for Antimicrobial Activity.
Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Hepatoprotective efficacy of silymarin-loaded metal-organic frameworks against CClPoultry science · 2026Article
- Tannic Acid and Copper-Modified ZIF-8 Metal Organic Framework as a Cefotaxime Delivery System for Antimicrobial ActivityTurkish journal of pharmaceutical sciences · 2026Article
- Zinc-Based Nanoparticles Reduce the Bacterial Burden and Protect Collagen in a Mouse Cutaneous Wound Model.ACS omega · 2026Article
- Fabrication of nogalamycin-loaded zeolitic imidazolate framework-8 metal-organic frameworks for promising drug carrier for lung cancer and antibacterial treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Mechanisms ofMedicina (Kaunas, Lithuania) · 2026Review
- Development and Characterization ofACS omega · 2025Article
- Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine.Pharmaceutics · 2025Review
- An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection.Bioactive materials · 2025Article
- Synergistic antibacterial activity of chitosan-polyethylene glycol nanocomposites films containing ZIF-8 and doxycycline.BMC biotechnology · 2025Article
- Antibacterial and wound healing effects of PEG-coated ciprofloxacin-loaded ZIF-8 nanozymes against ciprofloxacin-resistantFrontiers in pharmacology · 2025Article
- MOF@platelet-rich plasma antimicrobial GelMA dressing: structural characterization, bio-compatibility, and effect on wound healing efficacy.RSC advances · 2024Article
- Recent Progress in Multifunctional Stimuli-Responsive Combinational Drug Delivery Systems for the Treatment of Biofilm-Forming Bacterial Infections.Pharmaceutics · 2024Review
- Zeolitic imidazolate framework-8 encapsulated with Mo-based polyoxometalates as surfaces with antibacterial activity againstNanoscale advances · 2024Article
- Zeolitic Imidazolate Framework-8 Offers an Anti-Inflammatory and Antifungal Method in the Treatment ofInternational journal of nanomedicine · 2024Article
- Imidazoles as Serotonin Receptor Modulators for Treatment of Depression: Structural Insights and Structure-Activity Relationship Studies.Pharmaceutics · 2023Review
- Nanoparticles of Cerium-Doped Zeolitic Imidazolate Framework-8 Promote Soft Tissue Integration by Reprogramming the Metabolic Pathways of Macrophages.ACS biomaterials science & engineering · 2023Article
- Transition metal-based nanoparticles as potential antimicrobial agents: recent advancements, mechanistic, challenges, and future prospects.Discover nano · 2023Review
- Size Matters? A Comprehensive In Vitro Study of the Impact of Particle Size on the Toxicity of ZnO.Nanomaterials (Basel, Switzerland) · 2023Article
- Zeolitic Imidazolate Framework-8 (ZIF-8) as a Drug Delivery Vehicle for the Transport and Release of Telomerase Inhibitor BIBR 1532.Nanomaterials (Basel, Switzerland) · 2023Article
- Dissolved Carbon Dioxide: The Lifespan ofBiology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Numerous antimicrobial drugs have been prescribed to kill or inhibit the growth of microbes such as bacteria, fungi, and viruses. Despite the known therapeutic efficacy of these drugs, inefficient delivery could result in an inadequate therapeutic index and several side effects. In order to overcome this adversity, the present study investigated antibiotic drug loading in zeolitic imidazolate frameworks (ZIFs), in association with ZnO nanoparticles with known antimicrobial properties. In an economic synthesis method, the ZnO surface was first converted to ZIF-8 with 2-methylimidazole as a ligand, resulting in a ZnO@ZIF-8 structure. This system enables the high drug-loading efficiency (46%) of an antimicrobial drug, ciprofloxacin, within the pores of the ZIF-8. This association provides a control of the release of the active moieties, in simulated body-fluid conditions, with a maximum of 67% released in 96 h. The antibacterial activities of ZnO@ZIF-8 and CIP-ZnO@ZIF-8 were tested against the Gram-positive
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.