Evidence map›Paper›PMID 36678875›Full record

ArticlePharmaceutics2023

Effect of Solubilizing Group on the Antibacterial Activity of Heptamethine Cyanine Photosensitizers.

Olga Semenova, Dmytro Kobzev, Iryna Hovor, Melad Atrash, Faina Nakonechny, Olesia Kulyk, Andrii Bazylevich, Gary Gellerman, Leonid Patsenker

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Olga SemenovaDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Dmytro KobzevDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Iryna HovorDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Melad AtrashDepartment of Chemical Engineering, Ariel University, Ariel 40700, Israel.
Faina NakonechnyDepartment of Chemical Engineering, Ariel University, Ariel 40700, Israel.ORCID 0000-0002-8973-1322
Olesia KulykDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Andrii BazylevichDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Gary GellermanDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.ORCID 0000-0002-1336-8707
Leonid PatsenkerDepartment of Chemical Sciences, Ariel University, Ariel 40700, Israel.
Ariel University · IL

Funding

Center for Absorption in Science of the Ministry of Immigrant Absorption of Israel KAMEAGale Foundation NoIsrael Science Foundation 810/18
6 · The paper itself

Abstract

Antibiotic resistance of pathogenic bacteria dictates the development of novel treatment modalities such as antimicrobial photodynamic therapy (APDT) utilizing organic dyes termed photosensitizers that exhibit a high cytotoxicity upon light irradiation. Most of the clinically approved photosensitizers are porphyrins that are poorly excitable in the therapeutic near-IR spectral range. In contrast, cyanine dyes function well in the near-IR region, but their phototoxicity, in general, is very low. The introduction of iodine atoms in the cyanine molecules was recently demonstrated to greatly increase their phototoxicity. Herein, we synthesized a series of the new iodinated heptamethine cyanine dyes (

Indexed as

antimicrobial photodynamic therapyheavy-atom effectheptamethine cyaninesphotosensitizerssolubilizing groups

Identifiers

PMID36678875
PMCPMC9864305
OpenAlexW4315628449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.