Evidence map›Paper›PMID 36678771›Full record

ArticlePharmaceutics2022

Identification of Aryl Polyamines Derivatives as Anti-

Rubén Martín-Escolano, Daniel Molina-Carreño, Javier Martín-Escolano, Mª Paz Clares, Cristina Galiana-Roselló, Jorge González-García, Nuria Cirauqui, José M Llinares, María José Rosales, Enrique García-España and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Mechanistic Exploration ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Polyamine-Drug Conjugates: Do They Boost Drug Activity?Molecules (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Rubén Martín-EscolanoLaboratory of Molecular & Evolutionary Parasitology, RAPID Group, School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK.ORCID 0000-0002-6262-9344
Daniel Molina-CarreñoDepartment of Parasitology, University of Granada, Severo Ochoa s/n, 18071 Granada, Spain.
Javier Martín-EscolanoUnit of Infectious Diseases, Microbiology and Preventive Medicine, Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, 41013 Seville, Spain.
Mª Paz ClaresInstituto de Ciencia Molecular (ICMol), Departamento de Química Inorgánica, Universidad de Valencia, 46980 Paterna, Spain.
Cristina Galiana-RosellóInstituto de Ciencia Molecular (ICMol), Departamento de Química Inorgánica, Universidad de Valencia, 46980 Paterna, Spain.ORCID 0000-0003-1365-1323
Jorge González-GarcíaInstituto de Ciencia Molecular (ICMol), Departamento de Química Inorgánica, Universidad de Valencia, 46980 Paterna, Spain.ORCID 0000-0001-8994-1779
Nuria CirauquiEMBL Grenoble, 71 Avenue des Martyrs, 38000 Grenoble, France.
José M LlinaresInstituto de Ciencia Molecular (ICMol), Departamento de Química Inorgánica, Universidad de Valencia, 46980 Paterna, Spain.
María José RosalesDepartment of Parasitology, University of Granada, Severo Ochoa s/n, 18071 Granada, Spain.
Enrique García-EspañaInstituto de Ciencia Molecular (ICMol), Departamento de Química Inorgánica, Universidad de Valencia, 46980 Paterna, Spain.
Clotilde MarínDepartment of Parasitology, University of Granada, Severo Ochoa s/n, 18071 Granada, Spain.ORCID 0000-0002-4316-2742
Universitat de València · ESUniversidad de Granada · ESEuropean Molecular Biology Laboratory · FRInstituto de Biomedicina de Sevilla · ESUniversity of Kent · GB

Funding

Fundación Alfonso Martín Escudero Becas de investigación en universidades y centros en el extranjeroMinistry of Economy, Industry and Competitiveness CONSOLIDER CSD2010-00065Ministry of Economy, Industry and Competitiveness CTQ2017-90852-REDCMinistry of Economy, Industry and Competitiveness PID2019-110751RB-I00,Ministry of Economy, Industry and Competitiveness RED2018-102331-TUnidad de Excelencia María de Maeztu CEX2019-000919-M
6 · The paper itself

Abstract

Chagas disease (CD) is a tropical and potentially fatal infection caused by

Indexed as

aryl polyamineschagas diseasechemotherapydrug discoveryTrypanosoma cruzi

Identifiers

PMID36678771
PMCPMC9863987
OpenAlexW4313473016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.