Evidence map›Paper›PMID 36678696›Full record

ReviewPharmaceutics2022

Current Progress and Outlook of Nano-Based Hydrogel Dressings for Wound Healing.

Xiao Zhang, Pengyu Wei, Zhengyang Yang, Yishan Liu, Kairui Yang, Yuhao Cheng, Hongwei Yao, Zhongtao Zhang

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A critical overview of challenging roles of medicinal plants in improvement of wound healing technology.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2024
    Pooled it
  2. Article
  3. Nanosponge-integrated hydrogel ofFrontiers in pharmacology · 2026
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  14. How does oxytocin modulate human behavior?Molecular psychiatry · 2025
    Review
  15. Article
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  18. Assessing the efficacy of mesotherapy products: Ultra Exo Booster, and Ultra S Line Plus in hair growth: An ex vivo study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  19. Polymeric Nanohydrogel in Topical Drug Delivery System.International journal of nanomedicine · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiao ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.ORCID 0000-0002-9244-9344
Pengyu WeiDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Zhengyang YangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.ORCID 0000-0002-2640-9619
Yishan LiuDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Kairui YangJun Skincare Co., Ltd., Jiangsu Life Science & Technology Innovation Park, Nanjing 210093, China.
Yuhao ChengJun Skincare Co., Ltd., Jiangsu Life Science & Technology Innovation Park, Nanjing 210093, China.
Hongwei YaoDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Zhongtao ZhangDepartment of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

Funding

Clinical Center for Colorectal Cancer, Capital Medical University 1192070313National Key Technologies R&D Program 2015BAI13B09National Key Technologies R&D Program 2017YFC0110904
6 · The paper itself

Abstract

Wound dressing is an important tool for wound management. Designing wound dressings by combining various novel materials and drugs to optimize the peri-wound environment and promote wound healing is a novel concept. Hydrogels feature good ductility, high water content, and favorable oxygen transport, which makes them become some of the most promising materials for wound dressings. In addition, nanomaterials exhibit superior biodegradability, biocompatibility, and colloidal stability in wound healing and can play a role in promoting healing through their nanoscale properties or as carriers of other drugs. By combining the advantages of both technologies, several outstanding and efficient wound dressings have been developed. In this paper, we classify nano-based hydrogel dressings into four categories: hydrogel dressings loaded with a nanoantibacterial drug; hydrogel dressings loaded with oxygen-delivering nanomedicines; hydrogel dressings loaded with nanonucleic acid drugs; and hydrogel dressings loaded with other nanodelivered drugs. The design ideas, advantages, and challenges of these nano-based hydrogel wound dressings are reviewed and analyzed. Finally, we envisaged possible future directions for wound dressings in the context of relevant scientific and technological advances, which we hope will inform further research in wound management.

Indexed as

hydrogelsnanomedicinenanotechnologywound dressingswound healing

Identifiers

PMID36678696
PMCPMC9864871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.