Evidence map›Paper›PMID 36678690›Full record

ArticlePharmaceutics2022

Monocationic Chlorin as a Promising Photosensitizer for Antitumor and Antimicrobial Photodynamic Therapy.

Andrey V Kustov, Dmitry B Berezin, Vladimir P Zorin, Philipp K Morshnev, Natal'ya V Kukushkina, Mikhail A Krestyaninov, Tatyana V Kustova, Alexander I Strelnikov, Elena V Lyalyakina, Tatyana E Zorina and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Natural Chlorin eACS omega · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Photosensitizing effects and physicochemical properties of chlorophyll a derivatives with hydrophilic oligoethylene glycol fragments at the macrocycle periphery.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  7. Photo- and X-ray Induced Cytotoxicity of CeFMaterials (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Andrey V KustovG.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.ORCID 0000-0002-3553-6206
Dmitry B BerezinInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.ORCID 0000-0001-5814-9105
Vladimir P ZorinDepartment of Biophysics, Belarussian State University, 220030 Minsk, Belarus.
Philipp K MorshnevG.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Natal'ya V KukushkinaG.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Mikhail A KrestyaninovG.A. Krestov Institute of Solution Chemistry, Russian Academy of Sciences (ISC RAS), 153045 Ivanovo, Russia.
Tatyana V KustovaInstitute of Macroheterocyclic Compounds, Ivanovo State University of Chemistry and Technology (ISUCT), 153012 Ivanovo, Russia.
Alexander I StrelnikovDepartment of Departmental Surgery and Urology, Ivanovo State Medical Academy (ISMA), 153012 Ivanovo, Russia.
Elena V LyalyakinaIvanovo Regional Clinical Hospital (IRCH), 153000 Ivanovo, Russia.
Tatyana E ZorinaDepartment of Biophysics, Belarussian State University, 220030 Minsk, Belarus.
Olga B AbramovaLaboratory of Experimental Photodynamic Therapy, A.F. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, 249031 Obninsk, Russia.ORCID 0000-0003-3768-1439
Ekaterina A KozlovtsevaLaboratory of Experimental Photodynamic Therapy, A.F. Tsyb Medical Radiological Research Center-Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, 249031 Obninsk, Russia.
Ivanovo State University of Chemistry and Technology · RUBelarusian State University · BYMinistry of Health of the Russian Federation · RUInstitute of Solution Chemistry · RUIvanovo State Medical Academy · RU

Funding

Russian Science Foundation 21-13-00398
6 · The paper itself

Abstract

Cancer is one of the leading causes of death worldwide. Despite substantial progress in the understanding of tumor biology, and the appearance of new generations of targeted drugs and treatment techniques, the success achieved in this battle, with some notable exceptions, is still only moderate. Photodynamic therapy (PDT) is a successful but still underestimated therapeutic modality for treating many superficial cancers. In this paper, we focus on the extensive investigation of the monocationic chlorin photosensitizer (PS), considered here as a new photosensitizing agent for both antitumor and antimicrobial PDT. This monocationic chlorin PS (McChl) obtained from methylpheophorbide

Indexed as

antibiotic resistant microorganismsantimicrobial and antitumor efficacycancerchlorin photosensitizersphotodynamic therapyphysicochemical studysynthesis

Identifiers

PMID36678690
PMCPMC9863232
OpenAlexW4313260010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.