Evidence map›Paper›PMID 36678655›Full record

ArticlePharmaceutics2022

Itraconazole-Loaded Ufasomes: Evaluation, Characterization, and Anti-Fungal Activity against

Sara M Hashem, Mary K Gad, Hend M Anwar, Neveen M Saleh, Rehab N Shamma, Noha I Elsherif

Abstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
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  4. Article
  5. Nasal In-Situ Gels of BrijAAPS PharmSciTech · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara M HashemNational Organization for Drug Control and Research, Cairo 12622, Egypt.
Mary K GadNational Organization for Drug Control and Research, Cairo 12622, Egypt.
Hend M AnwarDepartment of Biochemistry, Egyptian Drug Authority, Cairo 12611, Egypt.ORCID 0000-0001-7940-7126
Neveen M SalehDepartment of Microbiology, Egyptian Drug Authority, Cairo 12611, Egypt.
Rehab N ShammaDepartment of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID 0000-0002-7635-6842
Noha I ElsherifDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Heliopolis University, Cairo 11785, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous obstacles challenge the treatment of fungal infections, including the uprising resistance and the low penetration of available drugs. One of the main active agents against fungal infections is itraconazole (ITZ), with activity against a broad spectrum of fungi while having few side effects. The aim of this study was to design ufasomes, oleic acid-based colloidal carriers, that could encapsulate ITZ to improve its penetration power. Employing a 2

Indexed as

Candida albicansitraconazolemicrobiologyoleic acidufasomes

Identifiers

PMID36678655
PMCPMC9862016

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.