Evidence map›Paper›PMID 36678653›Full record

ReviewPharmaceutics2022

Novel Development of Nanoparticles-A Promising Direction for Precise Tumor Management.

Dengke Zhang, Qingqing Tang, Juan Chen, Yanghui Wei, Jiawei Chen

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dengke ZhangDepartment of Surgery, The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Qingqing TangDepartment of Surgery, The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Juan ChenDepartment of Medicine & Rehabilitation, Tung Wah Eastern Hospital, Hong Kong, China.
Yanghui WeiDepartment of Surgery, The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.
Jiawei ChenDepartment of Surgery, The Eighth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0002-0895-9027

Funding

Futian Healthcare Research Project FTWS2020079
6 · The paper itself

Abstract

Although the clinical application of nanoparticles is still limited by biological barriers and distribution, with the deepening of our understanding of nanoparticles over the past decades, people are gradually breaking through the previous limitations in the diagnosis and treatment of tumors, providing novel strategies for clinical decision makers. The transition of nanoparticles from passive targeting to active tumor-targeting by abundant surface-modified nanoparticles is also a development process of precision cancer treatment. Different particles can be used as targeted delivery tools of antitumor drugs. The mechanism of gold nanoparticles inducing apoptosis and cycle arrest of tumor cells has been discovered. Moreover, the unique photothermal effect of gold nanoparticles may be widely used in tumor therapy in the future, with less side effects on surrounding tissues. Lipid-based nanoparticles are expected to overcome the blood-brain barrier due to their special characteristics, while polymer-based nanoparticles show better biocompatibility and lower toxicity. In this paper, we discuss the development of nanoparticles in tumor therapy and the challenges that need to be addressed.

Indexed as

antitumor drugnanoparticlestumor-targeting

Identifiers

PMID36678653
PMCPMC9862928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.