Evidence map›Paper›PMID 36678620›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

MAPK Cascade Signaling Is Involved in α-MMC Induced Growth Inhibition of Multiple Myeloma MM.1S Cells via G2 Arrest and Mitochondrial-Pathway-Dependent Apoptosis In Vitro.

Zi-Wei Cai, Ting Ye, Pei-Wen Jiang, Yu-Jiao Liao, Lin Wang, Qing-Liang Zhang, Wen-Qian Du, Min Huang, Ping Yang, Min-Hui Li

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. The Bioactive Properties of Carotenoids from LipophilicMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zi-Wei CaiSchool of Basic Medicine, Chengdu Medical College, Xindu 610500, China.
Ting YeSchool of Basic Medicine, Chengdu Medical College, Xindu 610500, China.
Pei-Wen JiangSchool of Basic Medicine, Chengdu Medical College, Xindu 610500, China.ORCID 0000-0001-6554-4592
Yu-Jiao LiaoSchool of Pharmacy, Chengdu Medical College, Xindu 610500, China.
Lin WangSchool of Pharmacy, Chengdu Medical College, Xindu 610500, China.
Qing-Liang ZhangSchool of Bioscience and Technology, Chengdu Medical College, Xindu 610500, China.
Wen-Qian DuSchool of Pharmacy, Chengdu Medical College, Xindu 610500, China.
Min HuangSchool of Pharmacy, Chengdu Medical College, Xindu 610500, China.
Ping YangSchool of Basic Medicine, Chengdu Medical College, Xindu 610500, China.
Min-Hui LiCenter of Scientific Research and Experiment, Chengdu Medical College, Xindu 610500, China.
Chengdu Medical College · CN

Funding

Sichuan Science and Technology Program 2020YFS0321Sichuan Science and Technology Program 2022NSFSC0690the Collaborative Innovation Center of Sichuan for Elderly Care and Health of Chengdu Medical College YLZBZ2007the National Undergraduates Innovating Experimentation Project of China 202213705001)the National Undergraduates Innovating Experimentation Project of China 202213705004the Open Fund of Development and Regeneration Key Laboratory of Sichuan Province SYS20-06
6 · The paper itself

Abstract

Multiple myeloma is a hematological malignancy characterized by the unrestricted proliferation of plasma cells that secrete monoclonal immunoglobulins in the bone marrow. Alpha-momorcharin (α-MMC) is a type I ribosome-inactivating protein extracted from the seeds of the edible plant

Indexed as

G2 arrestMAPK cascade signalingmitochondrial-pathway-dependent apoptosismultiple myelomaα-momorcharin

Identifiers

PMID36678620
PMCPMC9867419
OpenAlexW4316368934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.