Evidence map›Paper›PMID 36678597›Full record

ReviewPharmaceuticals (Basel, Switzerland)2023

Research Progress of Bioinspired Nanostructured Systems for the Treatment of Ocular Disorders.

Xuan Chen, Rui Yang, Jinyan Shen, Qingyu Huang, Zhifeng Wu

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Principles of Biocompatible Nanotube Design for High-Performance Biomaterials.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuan ChenDepartment of Ophthalmology, Wuxi Second People's Hospital, Nanjing Medical University, Wuxi 214002, China.
Rui YangResearch Institute for Reproductive Health and Genetic Diseases, Wuxi Maternity and Child Health Care Hospital, Wuxi School of Medicine, Jiangnan University, Wuxi 214002, China.
Jinyan ShenDepartment of Ophthalmology, Wuxi Second People's Hospital, Nanjing Medical University, Wuxi 214002, China.
Qingyu HuangDepartment of Ophthalmology, Wuxi Second People's Hospital, Nanjing Medical University, Wuxi 214002, China.
Zhifeng WuDepartment of Ophthalmology, Wuxi Second People's Hospital, Nanjing Medical University, Wuxi 214002, China.

Funding

Key project Foundation of Jiangsu health and Health Committee M2022105Natural Science Foundation of Jiangsu Province BK20221202Wuxi Taihu Talent Plan BJ2020074
6 · The paper itself

Abstract

How to enhance the bioavailability and prolong the residence time of drugs in the eye present the major barriers to traditional eye delivery. Nanotechnology has been widely used in ocular drug delivery systems because of its advantages of minimizing adverse reactions, decreasing the frequency of administration, prolonging the release time, and improving the bioavailability of the drug in the eye. As natural product-based nanostructured systems, bioinspired nanostructured systems have presented as less toxic, easy to prepare, and cost-effective and have potential application value in the field of nanotechnology. A systematic classification of bioinspired nanostructured systems based on their inspiration source and formulation and their brief applications in disease are presented here. A review of recent research progress of the bioinspired nanostructured systems for the treatment of the anterior and posterior segment of ocular disorders is then presented in detail. Finally, current challenges and future directions with regard to manufacturing bioinspired nanomaterials are provided.

Indexed as

anterior segmentbioinspirednanoocular disordersposterior segment

Identifiers

PMID36678597
PMCPMC9865244

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.