Evidence map›Paper›PMID 36678538›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Adjuvant Anti-PD-1 Immunotherapy versus Conventional Therapy for Stage III Melanoma: A Real-World Retrospective Cohort Study.

Tong Li, Yu Xu, Wei Sun, Wangjun Yan, Chunmeng Wang, Tu Hu, Xiaowei Zhang, Zhiguo Luo, Xin Liu, Yong Chen

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Adjuvant Therapy in Acral Melanoma: A Systematic Review.Clinical, cosmetic and investigational dermatology · 2024
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tong LiDepartment of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai 200032, China.ORCID 0000-0002-9987-8256
Yu XuDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Wei SunDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Wangjun YanDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.ORCID 0000-0001-9178-0687
Chunmeng WangDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Tu HuDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xiaowei ZhangDepartment of Internal Medicine of Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Zhiguo LuoDepartment of Internal Medicine of Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xin LiuDepartment of Internal Medicine of Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Yong ChenDepartment of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Fudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CN

Funding

LinGang laboratory "Seeking Distinguished Young Scholars" project LG-QS-202205-11National Natural Science Foundation of China 81802636Shanghai Science and Technology Development Funds 19411951700
6 · The paper itself

Abstract

The use of adjuvant therapy has provided survival benefits in patients with advanced melanoma. This study aimed to explore the recurrence and prognosis of the PD-1 inhibitor, conventional interferon (IFN), or observation (OBS) on resected stage III acral and cutaneous melanoma patients through a retrospective analysis. Patients with resected stage III melanoma at Fudan University Shanghai Cancer Center from 2017 to 2021 were enrolled with all of their clinicopathologic characteristics collected. They were divided into three groups: PD-1 inhibitor, IFN, and OBS. Survival analyses were performed to indicate the significance of different adjuvant therapies. A total of 199 patients were enrolled (PD-1 n = 126; IFN n = 31; and OBS n = 42), with their median follow-up times being 21 months, 24 months, and 49 months, respectively. The PD-1 inhibitor significantly improved relapse-free survival (

Indexed as

distant metastasis-free survivalinterferonmelanomaoverall survivalprogrammed cell death 1recurrence-free survival

Identifiers

PMID36678538
PMCPMC9867270
OpenAlexW4313413486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.