Evidence map›Paper›PMID 36678427›Full record

ArticlePathogens (Basel, Switzerland)2023

Potential Pathogenic and Opportunistic Oral Bacteria in Early Life: The Role of Maternal Factors in a Portuguese Population.

Mariana Fernandes, Maria João Azevedo, Carla Campos, Ana Filipa Ferreira, Álvaro Azevedo, Inês Falcão-Pires, Egija Zaura, Carla Ramalho, Joana Campos, Benedita Sampaio-Maia

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Mariana FernandesINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.
Maria João AzevedoINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0002-9117-4684
Carla CamposInstituto Português de Oncologia do Porto Francisco Gentil, 4200-072 Porto, Portugal.
Ana Filipa FerreiraCardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Álvaro AzevedoFaculdade de Medicina Dentária, Universidade do Porto, 4200-393 Porto, Portugal.ORCID 0000-0002-1014-6148
Inês Falcão-PiresCardiovascular R&D Centre-UnIC@RISE, Department of Surgery and Physiology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Egija ZauraAcademic Center for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands.ORCID 0000-0003-1432-6194
Carla Ramalhoi3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.
Joana CamposINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0002-4316-1520
Benedita Sampaio-MaiaINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0001-9368-8075
National Institute of Engineering, Technology and Innovation · PTUniversidade do Porto · PTAcademic Center for Dentistry Amsterdam · NLIPO Porto · PT

Funding

Biocodex (France) Biocodex National Call 2021 - PortugalEuropean Society of Clinical Microbiology and Infectious Diseases Research Grant 2021Fundação para a Ciência e Tecnologia SFRH/BD/144982/2019, SFRH/BD/138925/2018, POCI-01-0145-FEDER-029777/PTDC/MEC-MCI/29777/2017
6 · The paper itself

Abstract

In early life, maternal factors are of the utmost relevance for oral microbiome acquisition and maturation. Therefore, our study explored the impact of maternal factors, such as saliva and breastmilk colonization, cardiovascular risk factors (CRF), type of delivery, oral health, and caregiving habits on the prevalence of potential pathogenic and opportunistic oral bacteria in early life. A total of 26 healthy mothers, 23 mothers with CRF, and their 50 children were included and samples (child's oral swabs, mother's saliva, and breastmilk) were collected 4 to 12 weeks after delivery and inoculated in selective and differential media for detection of non-fastidious Gram-negative and Gram-positive bacteria to isolate potential pathogenic and opportunistic bacteria identified by MALDI-TOF MS (414 isolates). Within mother-child dyads, the same species were identified in 86% of the pairs and potential pathogenic microorganisms from the

Indexed as

cardiovascular riskmaternal oral healthmother–child microbiome transmissionopportunistic/pathogenic bacteriaoral microbiome

Identifiers

PMID36678427
PMCPMC9867333
OpenAlexW4313582491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.