Evidence map›Paper›PMID 36678416›Full record

ArticlePathogens (Basel, Switzerland)2022

Nodular Cutaneous Lesions in Immune-Compromised Hosts as a Clue for the Diagnosis of Disseminated Nocardiosis: From Bedside to Microbiological Identification.

Ilaria De Benedetto, Antonio Curtoni, Tommaso Lupia, Simone Mornese Pinna, Silvia Scabini, Guido Ricciardelli, Marco Iannaccone, Luigi Biancone, Massimo Boffini, Mauro Mangiapia and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Biliary microbiota in disease-free, obstructive and post-drainage biliary tracts.Frontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Ilaria De BenedettoDepartment of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-6524-0481
Antonio CurtoniMicrobiology Laboratory, "Città della Salute e della Scienza", Hospital of Turin, 10126 Turin, Italy.
Tommaso LupiaInfectious Diseases Unit, Cardinal Massaia Hospital, 14100 Asti, Italy.ORCID 0000-0002-3865-9519
Simone Mornese PinnaDepartment of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-0148-1075
Silvia ScabiniDepartment of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.
Guido RicciardelliMicrobiology Laboratory, "Città della Salute e della Scienza", Hospital of Turin, 10126 Turin, Italy.ORCID 0000-0002-9104-7247
Marco IannacconeMicrobiology Laboratory, "Città della Salute e della Scienza", Hospital of Turin, 10126 Turin, Italy.
Luigi BianconeDivision of Nephrology Dialysis and Transplantation, Department of Medical Sciences, "Città Della Salute e Della Scienza Hospital", University of Turin, 10126 Turin, Italy.
Massimo BoffiniDepartment of Cardiac Surgery, "Città Della Salute e Della Scienza Hospital", University of Turin, 10126 Turin, Italy.
Mauro MangiapiaDivision of Pneumonology, "Città della Salute e della Scienza Hospital", University of Turin, 10126 Turin, Italy.
Rossana CavalloMicrobiology Laboratory, "Città della Salute e della Scienza", Hospital of Turin, 10126 Turin, Italy.
Francesco Giuseppe De RosaDepartment of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-8338-0130
Silvia CorcioneDepartment of Medical Sciences, Infectious Diseases, University of Turin, 10126 Turin, Italy.
University of Turin · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Sanitaria Locale di Asti · ITTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsWe describe four cases of disseminated nocardiosis caused by

resultsCutaneous involvement is typically reported in immunocompetent hosts with primary cutaneous nocardiosis with multiple forms of manifestation; nonetheless, disseminated nocardiosis rarely involves the skin and subcutaneous tissues, and this occurs as a result of metastatic spread. Our cases were disseminated nocardiosis in which the metastatic cutaneous involvement, even if rare, provided a clue for the diagnosis.

conclusionsThe pathomorphosis of disseminated nocardiosis may have changed in the current years with more rapid spread due to advanced immunosuppression. For this reason, after clinical suspicion, the prompt start of an active targeted therapy based on rapid microbiological identification might potentially open the way to hopeful results, even in the most immune-compromised patients.

Indexed as

cutaneousdisseminatedMALDI-TOFNocardiaSOT

Identifiers

PMID36678416
PMCPMC9866504
OpenAlexW4313472532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.