Evidence map›Paper›PMID 36678384›Full record

ArticlePathogens (Basel, Switzerland)2022

Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Wild Birds and Live Bird Markets, Egypt.

Rabeh El-Shesheny, Yassmin Moatasim, Sara H Mahmoud, Yi Song, Ahmed El Taweel, Mokhtar Gomaa, Mina Nabil Kamel, Mohamed El Sayes, Ahmed Kandeil, Tommy T Y Lam and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Rabeh El-SheshenyCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.ORCID 0000-0002-8798-2240
Yassmin MoatasimCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Sara H MahmoudCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Yi SongState Key Laboratory of Emerging Infectious Diseases, School of Public Health, The University of Hong Kong, Hong Kong SAR, China.
Ahmed El TaweelCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Mokhtar GomaaCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Mina Nabil KamelCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Mohamed El SayesCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
Ahmed KandeilCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.ORCID 0000-0003-3253-6961
Tommy T Y LamState Key Laboratory of Emerging Infectious Diseases, School of Public Health, The University of Hong Kong, Hong Kong SAR, China.
Pamela P McKenzieDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Richard J WebbyDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-4397-7132
Ghazi KayaliHuman Link, Dubai 3O-01-BA380, United Arab Emirates.
Mohamed Ahmed AliCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza 12622, Egypt.
National Research Centre · EGSt. Jude Children's Research Hospital · USLaboratory of Data Discovery for Health · HK

Funding

Innovation and Technology Commission InnoHKNational Natural Science Foundation of China 31922087NIAID NIH HHS HHSN272201400006CNIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Clade 2.3.4.4 H5Nx influenza viruses have further diversified into several subclades. Sub-clade 2.3.4.4b H5N1 viruses have been widely circulating in wild birds and detected in Europe, Africa, Asia, and North America since October 2020. In this study, we report the first detection of highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses in wild birds and domestic ducks from live bird markets in Egypt. Phylogenetic analysis revealed that the Egyptian H5N1 virus retained the genomic composition of Eurasian strains. Mutations in the viral proteins associated with zoonotic potential and pathogenicity were detected in Egyptian isolates. Egypt is considered a hot spot for the evolution of the influenza virus, so active surveillance of avian influenza viruses in Egypt is warranted.

Indexed as

EgyptH5N1live bird marketspoultrywild birds

Identifiers

PMID36678384
PMCPMC9866256
OpenAlexW4312202253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.