Evidence map›Paper›PMID 36678258›Full record

Trial reportNutrients2023

Five Days of Tart Cherry Supplementation Improves Exercise Performance in Normobaric Hypoxia.

Masahiro Horiuchi, Yoshiyuki Fukuoka, Katsuhiro Koyama, Samuel J Oliver

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Masahiro HoriuchiFaculty of Sports and Life Science, National Institute of Fitness and Sports in KANOYA, Kagoshima 8912393, Japan.ORCID 0000-0001-5784-5694
Yoshiyuki FukuokaFaculty of Health and Sports Science, Doshisha University, Kyoto 6100394, Japan.
Katsuhiro KoyamaFaculty of Sport Science, Yamanashi Gakuin University, Yamanashi 4008575, Japan.ORCID 0000-0002-1571-4191
Samuel J OliverInstitute for Applied Human Physiology, School of Human and Behavioural Sciences, College of Human Sciences, Bangor University, Bangor LL57 2DG, UK.ORCID 0000-0002-9971-9546
Bangor University · GBDoshisha University · JPNational Institute of Fitness and Sports in Kanoya · JPYamanashi Gakuin University · JP

Funding

Japan Society for the Promotion of Science 18K11012
6 · The paper itself

Abstract

Previous studies have shown tart cherry (TC) to improve exercise performance in normoxia. The effect of TC on hypoxic exercise performance is unknown. This study investigated the effects of 5 days of tart cherry (TC) or placebo (PL) supplementation on hypoxic exercise performance. Thirteen healthy participants completed an incremental cycle exercise test to exhaustion (TTE) under two conditions: (i) hypoxia (13% O2) with PL and (ii) hypoxia with TC (200 mg anthocyanin per day for 4 days and 100 mg on day 5). Pulmonary gas exchange variables, peripheral arterial oxygen saturation (SpO2), deoxygenated hemoglobin (HHb), and tissue oxygen saturation (StO2) assessed by near-infrared spectroscopy in the vastus lateralis muscle were measured at rest and during exercise. Urinary 8-hydro-2′ deoxyguanosine (8-OHdG) excretion was evaluated pre-exercise and 1 and 5 h post-exercise. The TTE after TC (940 ± 84 s, mean ± standard deviation) was longer than after PL (912 ± 63 s, p < 0.05). During submaximal hypoxic exercise, HHb was lower and StO2 and SpO2 were higher after TC than PL. Moreover, a significant interaction (supplements × time) in urinary 8-OHdG excretion was found (p < 0.05), whereby 1 h post-exercise increases in urinary 8-OHdG excretion tended to be attenuated after TC. These findings indicate that short-term dietary TC supplementation improved hypoxic exercise tolerance, perhaps due to lower HHb and higher StO2 in the working muscles during submaximal exercise.

Indexed as

Prunus aviumDietary SupplementsExerciseExercise TestHumansHypoxiaMuscle, SkeletalOxygenOxygen ConsumptionQuadriceps MuscleOxygenantioxidantblood flowDNA damageO2 extractionoxidative stresstissue oxygenationvasodilation

Identifiers

PMID36678258
PMCPMC9864878
OpenAlexW4315781149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.