Evidence map›Paper›PMID 36677892›Full record

ArticleMolecules (Basel, Switzerland)2023

Evaluation of Antioxidant and Anticancer Activity of Mono- and Polyfloral Moroccan Bee Pollen by Characterizing Phenolic and Volatile Compounds.

Volkan Aylanc, Samar Larbi, Ricardo Calhelha, Lillian Barros, Feriel Rezouga, María Shantal Rodríguez-Flores, María Carmen Seijo, Asmae El Ghouizi, Badiaa Lyoussi, Soraia I Falcão and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Compositional and Biofunctional Properties ofFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Preliminary Characterization of MonofloralFood science & nutrition · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Diversity and Chemical Characterization of Apple (Antioxidants (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Volkan AylancCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-4060-766X
Samar LarbiCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.
Ricardo CalhelhaCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-6801-4578
Lillian BarrosCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-9050-5189
Feriel RezougaDépartement de Génies Biologique et Agroalimentaire, Université Libre de Tunis, 30 Avenue Kheireddine Pacha, Tunis 1002, Tunisia.
María Shantal Rodríguez-FloresFacultad de Ciencias, Universidad de Vigo, Campus as Lagoas, 36310 Vigo, Pontevedra, Spain.ORCID 0000-0002-2387-630X
María Carmen SeijoFacultad de Ciencias, Universidad de Vigo, Campus as Lagoas, 36310 Vigo, Pontevedra, Spain.ORCID 0000-0001-8289-6717
Asmae El GhouiziLaboratory Physiology-Pharmacology and Environmental Health, Faculty of Sciences Dhar El Mehraz, University Sidi Mohamed Ben Abdallah, Fez 30050, Morocco.
Badiaa LyoussiLaboratory Physiology-Pharmacology and Environmental Health, Faculty of Sciences Dhar El Mehraz, University Sidi Mohamed Ben Abdallah, Fez 30050, Morocco.
Soraia I FalcãoCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0003-3735-6951
Miguel Vilas-BoasCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.ORCID 0000-0002-8665-5280
Polytechnic Institute of Bragança · PTSidi Mohamed Ben Abdellah University · MATunisia Private University · TNUniversidade de Vigo · ESUniversidade do Porto · PT

Funding

European Regional Development Fund Norte-01-0145-FEDER-000042Fundação para a Ciência e Tecnologia 2021.07764.BD for Volkan Aylanc, and contracts through the individual and institutional scientific employment program-contract for Lillian Barros, Soraia I. Falcão and Ricardo CalhelhaFundação para a Ciência e Tecnologia UIDB/00690/2020, UIDP/00690/2020 and LA/P/0007/2021Programa de Desenvolvimento Rural 2014-2020 PDR2020-1.0.1-FEADER-031734
6 · The paper itself

Abstract

Bee pollen is frequently characterized as a natural source of bioactive components, such as phenolic compounds, which are responsible for its pharmaceutical potential and nutritional properties. In this study, we evaluated the bioactive compound contents of mono- and polyfloral bee pollen samples using spectroscopic and chromatographic methods and established links with their antioxidant and antitumor activity. The findings demonstrated that the botanical origin of bee pollen has a remarkable impact on its phenolic (3-17 mg GAE/g) and flavonoid (0.5-3.2 mg QE/g) contents. Liquid chromatography-mass spectrometry analysis revealed the presence of 35 phenolic and 13 phenylamide compounds in bee pollen, while gas chromatography-mass spectrometry showed its richness in volatiles, such as hydrocarbons, fatty acids, alcohols, ketones, etc. The concentration of bioactive compounds in each sample resulted in a substantial distinction in their antioxidant activity, DPPH (EC

Indexed as

AntioxidantsFlavonoidsAnimalsBeesGas Chromatography-Mass SpectrometryMass SpectrometryPhenolsPollenAntioxidantsFlavonoidsPhenolsantiradical capacityantitumor activitybee productsbioactive compoundsphenolic compoundsphenylamides

Identifiers

PMID36677892
PMCPMC9866838
OpenAlexW4316467851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.