Evidence map›Paper›PMID 36677776›Full record

ArticleMolecules (Basel, Switzerland)2023

Quantification and Validation of an HPLC Method for Low Concentrations of Apigenin-7-

Jin Seok Lee, Yu Ran Nam, Hyun Jong Kim, Woo Kyung Kim

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jin Seok LeeDepartment of Internal Medicine, Graduate School of Medicine, Dongguk University, 27 Dongguk-ro, Goyang 10326, Republic of Korea.ORCID 0000-0002-1909-8955
Yu Ran NamDepartment of Physiology, College of Medicine, Dongguk University, 123 Dongdae-ro, Gyeongju 38066, Republic of Korea.ORCID 0000-0001-7816-2585
Hyun Jong KimDepartment of Physiology, College of Medicine, Dongguk University, 123 Dongdae-ro, Gyeongju 38066, Republic of Korea.ORCID 0000-0002-6130-7028
Woo Kyung KimDepartment of Internal Medicine, Graduate School of Medicine, Dongguk University, 27 Dongguk-ro, Goyang 10326, Republic of Korea.ORCID 0000-0003-0359-3967

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we aimed to develop and validate a pretreatment method for separating and analyzing the small amounts of biomarkers contained in topical cream formulations. Analyzing semisolid formulations that contain low concentrations of active ingredients is difficult. Cream formulations containing an aqueous ethanol extract of 0.1% Agrimonia pilosa is an example. Approximately 0.0013% of apigenin-7-

Indexed as

AgrimoniaPlant ExtractsApigeninChromatography, High Pressure LiquidEthanolLiquid-Liquid ExtractionWaterApigeninapigenin-7-O-glucuronideEthanolPlant ExtractsWaterAgrimonia pilosaapigenin-7-O-glucuronidecreamHPLC-DADvalidation

Identifiers

PMID36677776
PMCPMC9866479

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.