Evidence map›Paper›PMID 36677740›Full record

ArticleMolecules (Basel, Switzerland)2023

Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences.

Florian Berthiol, Joseph Boissieras, Hugues Bonnet, Marie Pierrot, Christian Philouze, Jean-François Poisson, Anton Granzhan, Jérôme Dejeu, Eric Defrancq

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Florian BerthiolDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-2253-3401
Joseph BoissierasCNRS UMR9187, INSERM U1196, Institut Curie, PSL Research University, F-91405 Orsay, France.
Hugues BonnetDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.
Marie PierrotDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.
Christian PhilouzeDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.
Jean-François PoissonDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.
Anton GranzhanCNRS UMR9187, INSERM U1196, Institut Curie, PSL Research University, F-91405 Orsay, France.ORCID 0000-0002-0424-0461
Jérôme DejeuDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-2434-2959
Eric DefrancqDepartment of Molecular Chemistry (DCM), CNRS, UMR 5250, Université Grenoble-Alpes, 38000 Grenoble, France.ORCID 0000-0002-3911-6241
Centre National de la Recherche Scientifique · FR

Funding

Agence Nationale de la Recherche ANR-21-CE44-0005-02French National Centre for Scientific Research PRIME'80
6 · The paper itself

Abstract

During the last decade, the evidence for the biological relevance of i-motif DNA (i-DNA) has been accumulated. However, relatively few molecules were reported to interact with i-DNA, and a controversy concerning their binding mode, affinity, and selectivity persists in the literature. In this context, the cholestane derivative

Indexed as

CholestanesDNABase SequenceCircular DichroismLigandsPiperidinesCholestanesDNAIMC-48LigandsPiperidinesaffinitybio-layer interferometrycircular dichroismDNA ligandsIMC-48i-motif DNAsteroid derivatives

Identifiers

PMID36677740
PMCPMC9865601
OpenAlexW4315487079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.