Evidence map›Paper›PMID 36677666›Full record

ArticleMolecules (Basel, Switzerland)2023

Alkyl 4-Aryl-6-amino-7- phenyl-3-(phenylimino)-4,7-dihydro- 3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylates: Synthesis and Agrochemical Studies.

Victor V Dotsenko, Anna E Sinotsko, Vladimir D Strelkov, Ekaterina A Varzieva, Alena A Russkikh, Arina G Levchenko, Azamat Z Temerdashev, Nicolai A Aksenov, Inna V Aksenova

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. β-Ketoamides in Thieno[2,3-Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. New 6'-Amino-5'-cyano-2-oxo-1,2-dihydro-1'Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Victor V DotsenkoDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.ORCID 0000-0001-7163-0497
Anna E SinotskoDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.
Vladimir D StrelkovDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.
Ekaterina A VarzievaDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.ORCID 0000-0002-3204-8995
Alena A RusskikhDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.
Arina G LevchenkoDepartment of Organic Chemistry and Technologies, Kuban State University, 350040 Krasnodar, Russia.
Azamat Z TemerdashevDepartment of Analytical Chemistry, Kuban State University, 350040 Krasnodar, Russia.ORCID 0000-0002-8048-4740
Nicolai A AksenovDepartment of Chemistry, North Caucasus Federal University, 355017 Stavropol, Russia.
Inna V AksenovaDepartment of Chemistry, North Caucasus Federal University, 355017 Stavropol, Russia.
Kuban State University · RUNorth-Caucasus Federal University · RU

Funding

Russian Science Foundation 22-23-00458
6 · The paper itself

Abstract

The reaction between dithiomalondianilide (N,N'-diphenyldithiomalondiamide) and alkyl 3-aryl-2-cyanoacrylates in the presence of morpholine in the air atmosphere leads to the formation of alkyl 6-amino-4-aryl-7-phenyl-3-(phenylimino)-4,7-dihydro-3H-[1,2]dithiolo[3,4-b]- pyridine-5-carboxylates in 37-72% yields. The same compounds were prepared in 23-65% yields by ternary condensation of aromatic aldehydes, ethyl(methyl) cyanoacetate and dithiomalondianilide. The reaction mechanism is discussed. The structure of ethyl 6-amino-4-(4-methoxyphenyl)-7-phenyl-3-(phenylimino)-4,7-dihydro-3H-[1,2]dithiolo[3,4-b]pyridine-5-carboxylate was confirmed by X-ray crystallography. Two of the prepared compounds showed a moderate growth-stimulating effect on sunflower seedlings. Three of the new compounds were recognized as strong herbicide safeners with respect to herbicide 2,4-D in the laboratory and field experiments on sunflower.

Indexed as

[1,2]dithiolo[3,4-b]pyridinesactive methylene thioamidescyanoacetic estersdithiomalondianilideherbicide safenersMichael addition

Identifiers

PMID36677666
PMCPMC9864349
OpenAlexW4313894818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.