Evidence map›Paper›PMID 36677627›Full record

ArticleMolecules (Basel, Switzerland)2023

Selective Determination of Glutathione Using a Highly Emissive Fluorescent Probe Based on a Pyrrolidine-Fused Chlorin.

Francisco G Moscoso, Carla Queirós, Paula González, Tânia Lopes-Costa, Ana M G Silva, Jose M Pedrosa

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Porphyrin-Based Compounds: Synthesis and Application.Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francisco G MoscosoDepartamento de Sistemas Físicos, Químicos y Naturales, Universidad Pablo de Olavide, Ctra. Utrera km. 1, 41013 Seville, Spain.ORCID 0000-0002-6030-0449
Carla QueirósLAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, 4169-007 Porto, Portugal.ORCID 0000-0003-0485-8023
Paula GonzálezDepartamento de Sistemas Físicos, Químicos y Naturales, Universidad Pablo de Olavide, Ctra. Utrera km. 1, 41013 Seville, Spain.
Tânia Lopes-CostaDepartamento de Sistemas Físicos, Químicos y Naturales, Universidad Pablo de Olavide, Ctra. Utrera km. 1, 41013 Seville, Spain.ORCID 0000-0002-0297-6053
Ana M G SilvaLAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade do Porto, 4169-007 Porto, Portugal.ORCID 0000-0003-0393-1655
Jose M PedrosaDepartamento de Sistemas Físicos, Químicos y Naturales, Universidad Pablo de Olavide, Ctra. Utrera km. 1, 41013 Seville, Spain.ORCID 0000-0001-8750-6220

Funding

Agencia Española de Investigación PCI2020-112241Agencia Española de Investigación PID2019-110430 GB-C22Fundação para a Ciência e Tecnologia EXPL/QUI-OUT/1554/ 2021Fundação para a Ciência e Tecnologia UIDB/50006/2020Fundação para a Ciência e Tecnologia UIDP/50006/2020Regional Government of Andalusia P20 01258Regional Government of Andalusia UPO-1381028
6 · The paper itself

Abstract

We report the use of a carboxylated pyrrolidine-fused chlorin (TCPC) as a fluorescent probe for the determination of glutathione (GSH) in 7.4 pH phosphate buffer. TCPC is a very stable, highly emissive molecule that has been easily obtained from meso-tetrakis(4-methoxycarbonylphenyl) porphyrin (TCPP) through a 1,3-dipolar cycloaddition approach. First, we describe the coordination of TCPC with Hg(II) ions and the corresponding spectral changes, mainly characterized by a strong quenching of the chlorin emission band. Then, the TCPC-Hg

Indexed as

MercuryPorphyrinsFluorescent DyesGlutathioneIonsSpectrometry, FluorescencechlorinFluorescent DyesGlutathioneIonsMercuryPorphyrinscarboxylated pyrrolidine-fused chlorinfluorescenceglutathione detection

Identifiers

PMID36677627
PMCPMC9862258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.