Evidence map›Paper›PMID 36677566›Full record

ArticleMolecules (Basel, Switzerland)2023

Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner.

Chuan-Hsiu Liu, Mei-Ying Chen, Yueh-Hsiung Kuo, Jack Cheng, Li-Zhong Chang, Meng-Shiun Chang, Tsai-Ni Chuang, Wen-Tsong Hsieh, Yan-Ru Xiao, Bor-Tsang Wu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Antioxidants (Basel, Switzerland) · 2024
    Article
  5. Role of microglia in diabetic neuropathic pain.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Chuan-Hsiu LiuGraduate Institute of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Mei-Ying ChenGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Yueh-Hsiung KuoDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0001-5935-6755
Jack ChengGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Li-Zhong ChangGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Meng-Shiun ChangGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Tsai-Ni ChuangGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.
Wen-Tsong HsiehDepartment of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-2330-8898
Yan-Ru XiaoDepartment of Pharmacology, School of Medicine, China Medical University, Taichung 40402, Taiwan.
Bor-Tsang WuDepartment of Senior Service Management, National Taichung University of Science and Technology, Taichung City 40343, Taiwan.
Wei-Yong LinGraduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-8443-6180
Hsin-Ping LiuGraduate Institute of Acupuncture Science, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan.ORCID 0000-0002-2569-3072
China Medical University · TWAsia University · TWNational Taichung University of Science and Technology · TW

Funding

China Medical University CMU108-MF-61China Medical University CMU109-MF-110China Medical University CMU110-MF-92China Medical University CMU110-MF-96China Medical University CMU111-MF-65China Medical University Hospital DMR-111-147National Science and Technology Council Taiwan MOST 108-2320-B-039-031-MY3National Science and Technology Council Taiwan MOST 111-2314-B-039-017-MY3National Science and Technology Council Taiwan MOST 111-2320-B-039-032
6 · The paper itself

Abstract

Microglia are neuroglia in the brain with an innate immune function and participate in the progress of neurodegenerative diseases. Osthole (OST) is a coumarin derivative extracted from

Indexed as

CoumarinsMicrogliaAnimalsCell LineDrosophilaLipopolysaccharidesMiceNF-E2-Related Factor 2CoumarinsLipopolysaccharidesNF-E2-Related Factor 2ostholmicrogliaNRF2osthole

Identifiers

PMID36677566
PMCPMC9912252
OpenAlexW4313500510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.