Evidence map›Paper›PMID 36677536›Full record

ArticleMolecules (Basel, Switzerland)2023

Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base-Benzimidazole Hybrids with VEGFR-2 Inhibitory Activity.

Hany M Abd El-Lateef, Mohammed A I Elbastawesy, Tamer Mohamed Abdelghani Ibrahim, Mai M Khalaf, Mohamed Gouda, Mariam G F Wahba, Islam Zaki, Martha M Morcoss

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Recent progress in the exploitation of anti-cancer small molecules targeting angiogenesis.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hany M Abd El-LateefDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-6610-393X
Mohammed A I ElbastawesyDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
Tamer Mohamed Abdelghani IbrahimCommunity Engagement Development Administration, Vice-Presidency for Studies, Development and Community Service, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Mai M KhalafDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-0599-9928
Mohamed GoudaDepartment of Chemistry, College of Science, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-7864-4151
Mariam G F WahbaDepartment of Pharmacology and Toxicology, Faculty of pharmacy, Nahda University, Beni-Suef 62513, Egypt.
Islam ZakiPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt.ORCID 0000-0002-2026-7373
Martha M MorcossDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt.

Funding

King Faisal University 2084
6 · The paper itself

Abstract

A new series of Schiff-benzimidazole hybrids

Indexed as

Antineoplastic AgentsVascular Endothelial Growth Factor Receptor-2ApoptosisBenzimidazolesCell ProliferationDrug DesignDrug Screening Assays, AntitumorMolecular Docking SimulationMolecular StructureSchiff BasesSorafenibStructure-Activity RelationshipAntineoplastic AgentsBenzimidazolesSchiff BasesSorafenibVascular Endothelial Growth Factor Receptor-2anti-proliferativeapoptosisbenzimidazoledockinghybridsSchiffVEGFR

Identifiers

PMID36677536
PMCPMC9862622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.