Evidence map›Paper›PMID 36677521›Full record

ArticleMicroorganisms2023

Deletions across the SARS-CoV-2 Genome: Molecular Mechanisms and Putative Functional Consequences of Deletions in Accessory Genes.

Igor B Rogozin, Andreu Saura, Anastassia Bykova, Vyacheslav Brover, Vyacheslav Yurchenko

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  6. Review
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  8. Article
  9. The Mutational Landscape of SARS-CoV-2.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Igor B RogozinNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.ORCID 0000-0003-0802-4851
Andreu SauraLife Science Research Centre, Faculty of Science, University of Ostrava, 710 00 Ostrava, Czech Republic.
Anastassia BykovaLife Science Research Centre, Faculty of Science, University of Ostrava, 710 00 Ostrava, Czech Republic.
Vyacheslav BroverNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.ORCID 0000-0002-4980-7150
Vyacheslav YurchenkoLife Science Research Centre, Faculty of Science, University of Ostrava, 710 00 Ostrava, Czech Republic.ORCID 0000-0003-4765-3263
University of Ostrava · CZNational Institutes of Health · US

Funding

National Biomedical Information ServicesZIHLM200888 · NLM · NATIONAL LIBRARY OF MEDICINE · PI PALTOO, DINA · 2009 to 2025
$5200.7M
Intramural Research Program of the National Library of Medicine at the National Institutes of Health N/AMinistry of Education Youth and Sports SGS/PřF/2023
6 · The paper itself

Abstract

The analysis of deletions may reveal evolutionary trends and provide new insight into the surprising variability and rapidly spreading capability that SARS-CoV-2 has shown since its emergence. To understand the factors governing genomic stability, it is important to define the molecular mechanisms of deletions in the viral genome. In this work, we performed a statistical analysis of deletions. Specifically, we analyzed correlations between deletions in the SARS-CoV-2 genome and repetitive elements and documented a significant association of deletions with runs of identical (poly-) nucleotides and direct repeats. Our analyses of deletions in the accessory genes of SARS-CoV-2 suggested that there may be a hypervariability in

Indexed as

evolutionpalindromesrecombinationrecurrent deletionsreplicationtemplate switch

Identifiers

PMID36677521
PMCPMC9862619
OpenAlexW4316673196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.