ReviewMicroorganisms2022
Epidemiology of Fungal Periprosthetic Joint Infection: A Systematic Review of the Literature.
Review in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Non-intravenous Amphotericin B: A Review of Localized Administration Routes.Infectious diseases and therapy · 2026Review
- Two-stage revision combined with anti-infective therapy for mixed fungal and bacterial knee periprosthetic joint infection: a case report and literature review.BMC musculoskeletal disorders · 2026Review
- Candida albicans Periprosthetic Hip Infection Complicated by Recurrent Dislocations Following Revision Total Hip Arthroplasty: A Case Report.Journal of orthopaedic case reports · 2026Article
- Periprosthetic joint infection (PJI) due to candida tropicalis following total knee arthroplasty (TKA): A case report.IDCases · 2026Article
- The proportion of chronic periprosthetic joint infection patients withJournal of bone and joint infection · 2026Article
- Cemented versus uncemented fixation of femoral components in 2-stage hip revision arthroplasty to treat periprosthetic joint infection: a cohort study on 94 patients comparing the risks for relapse and reoperation.Acta orthopaedica · 2025Article
- Prosthetic knee joint infection caused by Aspergillus penicillioides: a case report.BMC infectious diseases · 2025Article
- Recalcitrant Fungal Prosthetic Joint Infection of the Knee Cleared Using Voriconazole via Intra-Articular Catheters.Clinical case reports · 2025Article
- What is the most advantageous lavage solution to use for fungal prosthetic joint infections.Journal of clinical orthopaedics and trauma · 2025Article
- A One- or Two-Stage Revision of Fungal Prosthetic Joint Infection: A Review of Current Knowledge, Pitfalls and Recommendations.Antibiotics (Basel, Switzerland) · 2025Review
- Outcome Predictors ofOpen forum infectious diseases · 2025Article
- A Narrative Review of Fungal Periprosthetic Joint Infections of the Hip and Knee: Risk Factors, Microbiological Profiles, and Treatment Challenges.Journal of clinical medicine · 2025Review
- In Vitro and In Vivo Translational Insights into the Intraoperative Use of Antiseptics and Lavage Solutions Against Microorganisms Causing Orthopedic Infections.International journal of molecular sciences · 2024Article
- Controlled Delivery of Ketoconazole an Antifungal Agent from Uncemented Titanium Using a Layer-by-Layer Technique.ACS omega · 2024Article
- Candidemia in an Orthopedic Patient Detected Coincidentally by Peripheral Blood Smear.Diagnostics (Basel, Switzerland) · 2024Article
- Fungal Shoulder Periprosthetic Infections: A Systematic Review.Journal of clinical medicine · 2024Review
- Diagnostic Performance of a Molecular Assay in Synovial Fluid Targeting Dominant Prosthetic Joint Infection Pathogens.Microorganisms · 2024Article
- Modern Microbiological Methods to Detect Biofilm Formation in Orthopedy and Suggestions for Antibiotic Therapy, with Particular Emphasis on Prosthetic Joint Infection (PJI).Microorganisms · 2024Review
- Delayed Diagnosis ofArthroplasty today · 2024Article
- Joint aspiration for diagnosis of chronic periprosthetic joint infection: when, how, and what tests?Arthroplasty (London, England) · 2023Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungal prosthetic joint infection (fPJI) is a rare complication; nonetheless, it represents a significant diagnostic and therapeutic challenge. There are no official guidelines on the most effective approach to identify and treat fPJIs. This systematic review aims to review the current literature on fPJI management and provide a comprehensive overview of this topic, especially from an epidemiologic point of view. Studies eligible for this systematic review were identified through an electronic systematic search of PubMed, Scopus, and Web of Science until 30 September 2022. Further references were obtained by cross-referencing. Sixty-three studies met the inclusion criteria, reporting on 372 cases of fPJI; such cases were described mostly in case reports and small case series with only a few larger cohort studies. Diagnosis of fPJI is challenging because of its chronic and indolent clinical course; it is further complicated by the technical difficulty of harvesting fungal cultures. A two-stage revision was the primary procedure in 239 (64.2%) patients whereas DAIR and one-stage approaches were reported in 30 (8.0%) and 18 (4.8 %) cases. In conclusion, our study highlights the heterogeneity of the reported treatments of fPJI, particularly in terms of medical management. With concern to a surgical approach, a two-stage revision arthroplasty is generally suggested, considering fPJI a delayed or late infection. The need for multicenter, prospective studies to provide standardized protocols and improve the treatment of fungal PJI clearly emerges.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.