Evidence map›Paper›PMID 36677221›Full record

ArticleMicromachines2023

Trapping of a Single Microparticle Using AC Dielectrophoresis Forces in a Microfluidic Chip.

Yanjuan Wang, Ning Tong, Fengqi Li, Kai Zhao, Deguang Wang, Yijie Niu, Fengqiang Xu, Jiale Cheng, Junsheng Wang

Abstract read
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yanjuan WangSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.ORCID 0000-0003-0812-5732
Ning TongSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.
Fengqi LiSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.
Kai ZhaoLiaoning Key Laboratory of Marine Sensing and Intelligent Detection, College of Information Science and Technology, Dalian Maritime University, Dalian 116026, China.ORCID 0000-0002-2377-6165
Deguang WangSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.
Yijie NiuSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.
Fengqiang XuSoftware Institute, Dalian Jiaotong University, Dalian 116028, China.
Jiale ChengLiaoning Key Laboratory of Marine Sensing and Intelligent Detection, College of Information Science and Technology, Dalian Maritime University, Dalian 116026, China.
Junsheng WangLiaoning Key Laboratory of Marine Sensing and Intelligent Detection, College of Information Science and Technology, Dalian Maritime University, Dalian 116026, China.

Funding

China Postdoctoral Science Foundation 2021M690500Dalian high level Talents Innovation Support Plan 2019RJ08Dalian key field innovation team 2021RT05Dalian Science and Technology Innovation Fund 2021JJ12GX014Fundamental Research Funds for the Central Universities of China 3132022247Key R&D projects in Liaoning Province 2022JH2/101300269Key R&D projects in Liaoning Province 2022JH2/10700012Liaoning Province "Unveiling the list and Taking the lead" project 85210038National Natural Science Foundation of China 52171343National Natural Science Foundation of China 61902051Startup Research Foundation for Talents of Dalian Maritime University 02500352
6 · The paper itself

Abstract

Precise trap and manipulation of individual cells is a prerequisite for single-cell analysis, which has a wide range of applications in biology, chemistry, medicine, and materials. Herein, a microfluidic trapping system with a 3D electrode based on AC dielectrophoresis (DEP) technology is proposed, which can achieve the precise trapping and release of specific microparticles. The 3D electrode consists of four rectangular stereoscopic electrodes with an acute angle near the trapping chamber. It is made of Ag-PDMS material, and is the same height as the channel, which ensures the uniform DEP force will be received in the whole channel space, ensuring a better trapping effect can be achieved. The numerical simulation was conducted in terms of electrode height, angle, and channel width. Based on the simulation results, an optimal chip structure was obtained. Then, the polystyrene particles with different diameters were used as the samples to verify the effectiveness of the designed trapping system. The findings of this research will contribute to the application of cell trapping and manipulation, as well as single-cell analysis.

Indexed as

dielectrophoresismanipulationmicrofluidic chiptrap

Identifiers

PMID36677221
PMCPMC9863554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.