ReviewMetabolites2023
Different Types of Glucocorticoids to Evaluate Stress and Welfare in Animals and Humans: General Concepts and Examples of Combined Use.
Review in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 27 citations in OpenAlex.
- A Validated LC-MS/MS Method for Simultaneous Determination of Cortisol and Cortisone in Grey Wolf Hair for Application in Ecological Studies.Molecules (Basel, Switzerland) · 2026Article
- Satellite and ground-level residential greenness and hair steroid hormones during pregnancy.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Adrenocortical Adenocarcinoma in a Syrian Golden Hamster (Mesocricetus auratus) With Suspected Hyperadrenocorticism.Veterinary medicine and science · 2026Article
- Beyond cortisol: evaluating serotonin, brain-derived neurotrophic factor, and oxytocin as indicators of equine welfare across three training regimens.BMC veterinary research · 2026Article
- Prolonged social isolation promotes depressive-like behavior in male and female mice, with sex-related differences in the stress response.Biology of sex differences · 2026Article
- Spikes in the data: biological validation and applications of an assay for detecting faecal glucocorticoid metabolites in Western European hedgehogs (Conservation physiology · 2026Article
- Traditional Transportation Methods and Their Influence on Local Chicken Welfare, Behavior, and Blood Profiles: A Policy Considerations.Veterinary sciences · 2025Article
- Getting used to it? Stress of repeated management procedures in semi-domesticated reindeer.BMC veterinary research · 2025Article
- How does chronic unpredictable mild stress affect the number of mature oocytes? An experimental study.International journal of reproductive biomedicine · 2025Article
- Dermal glucocorticoids are uncoupled from stress physiology and infection.Conservation physiology · 2025Article
- Use of thermal imaging to collect fresh faeces for non-invasive evaluation of stress levels in the European hare (Frontiers in veterinary science · 2025Article
- The Integrative Life History of Maternal Effects.Integrative and comparative biology · 2024Review
- Evaluating quackery formulations: LC-MS/MS based method for detecting glucocorticoid content.Toxicology reports · 2024Article
- Short Immobilization in a Sling Does Not Lead to Increased Salivary Cortisol Levels in Pigs.Animals : an open access journal from MDPI · 2024Article
- Faecal Glucocorticoid Metabolites and Hair Cortisone/Cortisol Measurements in Domestic Pigs Exposed to Road Transportation and Dexamethasone Treatment.Animals : an open access journal from MDPI · 2024Article
- Neurobiological Implications of Chronic Stress and Metabolic Dysregulation in Inflammatory Bowel Diseases.Diseases (Basel, Switzerland) · 2024Review
- Article
- A validated LC-MS/MS method for simultaneous determination of key glucocorticoids in animal hair for applications in conservation biology.Scientific reports · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
The main glucocorticoids involved in the stress response are cortisol and cortisone in most mammals and corticosterone in birds and rodents. Therefore, these analytes are currently the biomarkers more frequently used to evaluate the physiological response to a stressful situation. In addition, "total glucocorticoids", which refers to the quantification of various glucocorticoids by immunoassays showing cross-reactivity with different types of glucocorticoids or related metabolites, can be measured. In this review, we describe the characteristics of the main glucocorticoids used to assess stress, as well as the main techniques and samples used for their quantification. In addition, we analyse the studies where at least two of the main glucocorticoids were measured in combination. Overall, this review points out the different behaviours of the main glucocorticoids, depending on the animal species and stressful stimuli, and shows the potential advantages that the measurement of at least two different glucocorticoid types can have for evaluating welfare.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.