Evidence map›Paper›PMID 36676923›Full record

ArticleMembranes2023

Fabrication of Mechanically Enhanced, Suturable, Fibrous Hydrogel Membranes.

Constantinos Voniatis, Olivér Závoti, Kenigen Manikion, Bálint Budavári, Angela Jedlovszky Hajdu

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Biomineralized MnOPharmaceutics · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Constantinos VoniatisDepartment of Surgery, Transplantation and Gastroenterology, Semmelweis University, 1082 Budapest, Hungary.ORCID 0000-0002-5454-0120
Olivér ZávotiLaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary.ORCID 0000-0002-8243-3402
Kenigen ManikionLaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary.
Bálint BudaváriLaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary.
Angela Jedlovszky HajduLaboratory of Nanochemistry, Department of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary.
Semmelweis University · HU

Funding

New national excellence program of the ministry for culture and innovation from the source of the national research, development and innovation fund. ÚNKP-22-4-II-SE-31
6 · The paper itself

Abstract

Poly(vinyl-alcohol) hydrogels have already been successfully utilised as drug carrier systems and tissue engineering scaffolds. However, lacking mechanical strength and suturability hinders any prospects for clinical and surgical applications. The objective of this work was to fabricate mechanically robust PVA membranes, which could also withstand surgical manipulation and suturing. Electrospun membranes and control hydrogels were produced with 61 kDa PVA. Using a high-speed rotating cylindrical collector, we achieved fibre alignment (fibre diameter: 300 ± 50 nm). Subsequently, we created multilayered samples with different orientations to achieve multidirectional reinforcement. Finally, utilising glutaraldehyde as a cross-linker, we created insoluble fibrous-hydrogel membranes. Mechanical studies were performed, confirming a fourfold increase in the specific loading capacities (from 0.21 to 0.84 Nm

Indexed as

electrospinninggel-fibreshydrogelpoly(vinyl-alcohol)surgical

Identifiers

PMID36676923
PMCPMC9867240
OpenAlexW4316664443

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.