Evidence map›Paper›PMID 36676186›Full record

ArticleLife (Basel, Switzerland)2023

Gamma Knife Radiosurgery Irradiation of Surgical Cavity of Brain Metastases: Factor Analysis and Gene Mutations.

Yi-Han Huang, Huai-Che Yang, Chi-Lu Chiang, Hsiu-Mei Wu, Yung-Hung Luo, Yong-Sin Hu, Chung-Jung Lin, Wen-Yuh Chung, Cheng-Ying Shiau, Wan-Yuo Guo and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yi-Han HuangDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Huai-Che YangDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-4949-5417
Chi-Lu ChiangSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Hsiu-Mei WuSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yung-Hung LuoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-4194-162X
Yong-Sin HuSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-4786-0791
Chung-Jung LinSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Wen-Yuh ChungDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-9343-6289
Cheng-Ying ShiauSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Wan-Yuo GuoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Cheng-Chia LeeDepartment of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei 112, Taiwan.ORCID 0000-0003-4691-2913
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Surgical resection for the removal of brain metastases often fails to prevent tumor recurrence within the surgical cavity; hence, researchers are divided as to the benefits of radiation treatment following surgical resection. This retrospective study assessed the effects of post-operative stereotactic radiosurgery (SRS) on local tumor control and overall survival. (2) Methods: This study examined the demographics, original tumor characteristics, and surgical outcomes of 97 patients who underwent Gamma Knife Radiosurgery (GKRS) treatment (103 brain metastases). Kaplan-Meier plots and Cox regression were used to correlate clinical features to tumor control and overall survival. (3) Results: The overall tumor control rate was 75.0% and overall 12-month survival was 89.6%. Tumor control rates in the radiation group versus the non-radiation group were as follows: 12 months (83.1% vs. 57.7%) and 24 months (66.1% vs. 50.5%). During the 2-year follow-up period after SRS, the intracranial response rate was higher in the post-craniotomy radiation group than in the non-radiation group (

Indexed as

brain metastasisGamma Kniferadiosurgerysurgical cavitysurvivaltumor control

Identifiers

PMID36676186
PMCPMC9864800
OpenAlexW4316466531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.