Evidence map›Paper›PMID 36676144›Full record

ArticleLife (Basel, Switzerland)2023

Taxonomic Assignment-Based Genome Reconstruction from Apical Periodontal Metagenomes to Identify Antibiotic Resistance and Virulence Factors.

K Swapna Kumari, Sangita Dixit, Mahendra Gaur, Dibyajyoti Uttameswar Behera, Suchanda Dey, Rajesh Kumar Sahoo, Patitapaban Dash, Enketeswara Subudhi

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

K Swapna KumariInstitute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.
Sangita DixitCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.ORCID 0000-0003-3954-8527
Mahendra GaurDrug Development and Analysis Laboratory, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.ORCID 0000-0001-5800-7668
Dibyajyoti Uttameswar BeheraCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.
Suchanda DeyCentre for Biotechnology, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.
Rajesh Kumar SahooInstitute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.
Patitapaban DashInstitute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.ORCID 0000-0003-4637-4684
Enketeswara SubudhiInstitute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar 751003, India.ORCID 0000-0003-0571-6940
Siksha O Anusandhan University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary apical periodontitis occurs due to various insults to the dental pulp including microbial infections, physical and iatrogenic trauma, whereas inadequate elimination of intraradicular infection during root canal treatment may lead to secondary apical periodontitis. We explored the complex intra-radicular microbial communities and their functional potential through genome reconstruction. We applied shotgun metagenomic sequencing, binning and functional profiling to identify the significant contributors to infection at the acute and chronic apical periodontal lesions. Our analysis revealed the five classified clusters representing

Indexed as

apical periodontitisbinningdiversityEnterobactermetagenomemulti-drug resistancePseudomonasroot canal infections

Identifiers

PMID36676144
PMCPMC9861942
OpenAlexW4313898779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.